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Synthesis and Biological Evaluation of Novel Triazine Derivatives as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors. , Wang X ., J Med Chem. August 26, 2021; 64 (16): 12379-12396.
Modeling human congenital disorders with neural crest developmental defects using patient-derived induced pluripotent stem cells. , Okuno H., Regen Ther. August 24, 2021; 18 275-280.
Organization of DNA Replication Origin Firing in Xenopus Egg Extracts: The Role of Intra-S Checkpoint. , Ciardo D., Genes (Basel). August 9, 2021; 12 (8):
Unique variants in CLCN3, encoding an endosomal anion/proton exchanger, underlie a spectrum of neurodevelopmental disorders. , Duncan AR., Am J Hum Genet. August 5, 2021; 108 (8): 1450-1465.
GluN2A and GluN2B NMDA receptors use distinct allosteric routes. , Tian M., Nat Commun. August 5, 2021; 12 (1): 4709.
Retinol binding protein 1 affects Xenopus anterior neural development via all-trans retinoic acid signaling. , Flach H., Dev Dyn. August 1, 2021; 250 (8): 1096-1112.
Heterochromatin protein 1 beta regulates neural and neural crest development by repressing pluripotency-associated gene pou5f3.2/oct25 in Xenopus. , Tien CL., Dev Dyn. August 1, 2021; 250 (8): 1113-1124.
Protein kinase D1 variant associated with human epilepsy and peripheral nerve hypermyelination. , Omer S., Clin Genet. August 1, 2021; 100 (2): 176-186.
Bisphenols disrupt thyroid hormone (TH) signaling in the brain and affect TH-dependent brain development in Xenopus laevis. , Niu Y., Aquat Toxicol. August 1, 2021; 237 105902.
Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod. , Alejevski F., Open Biol. August 1, 2021; 11 (8): 210065.
Glycine agonism in ionotropic glutamate receptors. , Stroebel D., Neuropharmacology. August 1, 2021; 193 108631.
Role of matrix metalloproteinase-9 in neurodevelopmental deficits and experience-dependent plasticity in Xenopus laevis. , Gore SV., Elife. July 20, 2021; 10
Early Developmental Exposure to Fluoxetine and Citalopram Results in Different Neurodevelopmental Outcomes. , Liu K ., Neuroscience. July 15, 2021; 467 110-121.
Rab7 is required for mesoderm patterning and gastrulation in Xenopus. , Kreis J., Biol Open. July 15, 2021; 10 (7):
Resolving different presynaptic activity patterns within single olfactory glomeruli of Xenopus laevis larvae. , Topci R., Sci Rep. July 9, 2021; 11 (1): 14258.
Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons. , Hahn I., PLoS Genet. July 6, 2021; 17 (7): e1009647.
Axon terminals control endolysosome diffusion to support synaptic remodelling. , Terni B., Life Sci Alliance. July 5, 2021; 4 (8):
The role of cell lineage in the development of neuronal circuitry and function. , Hartenstein V., Dev Biol. July 1, 2021; 475 165-180.
DLG5 variants are associated with multiple congenital anomalies including ciliopathy phenotypes. , Marquez J ., J Med Genet. July 1, 2021; 58 (7): 453-464.
Three-dimensional folding dynamics of the Xenopus tropicalis genome. , Niu L., Nat Genet. July 1, 2021; 53 (7): 1075-1087.
Synthetic resin acid derivatives selectively open the hKV 7.2/7.3 channel and prevent epileptic seizures. , Ottosson NE., Epilepsia. July 1, 2021; 62 (7): 1744-1758.
Ciliogenesis and autophagy are coordinately regulated by EphA2 in the cornea to maintain proper epithelial architecture. , Kaplan N., Ocul Surf. July 1, 2021; 21 193-205.
Recurrent seizure-related GRIN1 variant: Molecular mechanism and targeted therapy. , Xu Y ., Ann Clin Transl Neurol. July 1, 2021; 8 (7): 1480-1494.
Mutations in SIX1 Associated with Branchio-oto-Renal Syndrome (BOR) Differentially Affect Otic Expression of Putative Target Genes. , Mehdizadeh T., J Dev Biol. June 30, 2021; 9 (3):
Fosl1 is vital to heart regeneration upon apex resection in adult Xenopus tropicalis. , Wu HY., NPJ Regen Med. June 29, 2021; 6 (1): 36.
The gastrin-releasing peptide/bombesin system revisited by a reverse-evolutionary study considering Xenopus. , Hirooka A., Sci Rep. June 25, 2021; 11 (1): 13315.
The highly conserved FOXJ1 target CFAP161 is dispensable for motile ciliary function in mouse and Xenopus. , Beckers A., Sci Rep. June 25, 2021; 11 (1): 13333.
The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra. , Ziegler B., BMC Biol. June 9, 2021; 19 (1): 120.
Application of Recombinant Rabies Virus to Xenopus Tadpole Brain. , Faulkner RL., eNeuro. June 7, 2021; 8 (4):
Identification of PUFA interaction sites on the cardiac potassium channel KCNQ1. , Yazdi S., J Gen Physiol. June 7, 2021; 153 (6):
Insights from a vertebrate model organism on the molecular mechanisms of whole-body dehydration tolerance. , Luu BE., Mol Cell Biochem. June 1, 2021; 476 (6): 2381-2392.
The Use of Xenopus for Cell Biology Applications. , Philpott A ., Cold Spring Harb Protoc. June 1, 2021; 2021 (6):
Anaplastic lymphoma kinase (alk), a neuroblastoma associated gene, is expressed in neural crest domains during embryonic development of Xenopus. , Moreno MM., Gene Expr Patterns. June 1, 2021; 40 119183.
Altering metabolite distribution at Xenopus cleavage stages affects left- right gene expression asymmetries. , Onjiko RM., Genesis. June 1, 2021; 59 (5-6): e23418.
Thyroid Disrupting Chemicals in Mixture Perturb Thymocyte Differentiation in Xenopus laevis Tadpoles. , McGuire CC., Toxicol Sci. May 27, 2021; 181 (2): 262-272.
The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus. , Zhang F., Proc Natl Acad Sci U S A. May 18, 2021; 118 (20):
Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects. , Lin Y., Proc Natl Acad Sci U S A. May 18, 2021; 118 (20):
Kindlin2 regulates neural crest specification via integrin-independent regulation of the FGF signaling pathway. , Wang H., Development. May 15, 2021; 148 (10):
Mapping single-cell atlases throughout Metazoa unravels cell type evolution. , Tarashansky AJ., Elife. May 4, 2021; 10
Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates. , Bright AR., EMBO J. May 3, 2021; 40 (9): e104913.
Effects of Copper on the Neuromasts of Xenopus Laevis. , Krupa PM., Arch Environ Contam Toxicol. May 1, 2021; 80 (4): 769-778.
Chronic Exposure to Two Gestagens Differentially Alters Morphology and Gene Expression in Silurana tropicalis. , Thomson P., Arch Environ Contam Toxicol. May 1, 2021; 80 (4): 745-759.
The Negative Allosteric Modulator EU1794-4 Reduces Single-Channel Conductance and Ca2+ Permeability of GluN1/GluN2A N-Methyl-d-Aspartate Receptors. , Perszyk RE., Mol Pharmacol. May 1, 2021; 99 (5): 399-411.
Molecular Regulation of Betulinic Acid on α3β4 Nicotinic Acetylcholine Receptors. , Lee S., Molecules. May 1, 2021; 26 (9):
Neurotoxic and convulsant effects induced by jack bean ureases on the mammalian nervous system. , Almeida CGM., Toxicology. April 30, 2021; 454 152737.
WIN55,212-2, a Dual Modulator of Cannabinoid Receptors and G Protein-Coupled Inward Rectifier Potassium Channels. , An D., Biomedicines. April 28, 2021; 9 (5):
Antimicrobial Bombinin-like Peptide 3 Selectively Recognizes and Inserts into Bacterial Biomimetic Bilayers in Multiple Steps. , Annaval T., J Med Chem. April 22, 2021; 64 (8): 5185-5197.
Image motion with color contrast suffices to elicit an optokinetic reflex in Xenopus laevis tadpoles. , Knorr AG., Sci Rep. April 19, 2021; 11 (1): 8445.
Bioelectric signaling: Reprogrammable circuits underlying embryogenesis, regeneration, and cancer. , Levin M ., Cell. April 15, 2021;
Basmisanil, a highly selective GABAA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man. , Hipp JF., Sci Rep. April 8, 2021; 11 (1): 7700.