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Mutation affecting the conserved acidic WNK1 motif causes inherited hyperkalemic hyperchloremic acidosis. , Louis-Dit-Picard H., J Clin Invest. December 1, 2020; 130 (12): 6379-6394.
WNK- SPAK- NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4. , Chávez-Canales M., Hypertension. November 1, 2014; 64 (5): 1047-53.
Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent process. , Castañeda-Bueno M., Proc Natl Acad Sci U S A. May 15, 2012; 109 (20): 7929-34.
A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo. , Oi K., Biol Open. February 15, 2012; 1 (2): 120-7.
Rare mutations in SLC12A1 and SLC12A3 protect against hypertension by reducing the activity of renal salt cotransporters. , Acuña R., J Hypertens. March 1, 2011; 29 (3): 475-83.
Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway. , Rozansky DJ., J Clin Invest. September 1, 2009; 119 (9): 2601-12.
A novel protein kinase signaling pathway essential for blood pressure regulation in humans. , Kahle KT., Trends Endocrinol Metab. April 1, 2008; 19 (3): 91-5.
Cotransporters, WNKs and hypertension: an update. , Flatman PW., Curr Opin Nephrol Hypertens. March 1, 2008; 17 (2): 186-92.
WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis. , Rinehart J., Proc Natl Acad Sci U S A. November 15, 2005; 102 (46): 16777-82.
WNK kinases and the control of blood pressure. , Cope G., Pharmacol Ther. May 1, 2005; 106 (2): 221-31.
[WNK1 and WNK4, new players in salt and water homeostasis] , Hadchouel J., Med Sci (Paris). January 1, 2005; 21 (1): 55-60.
WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia. , Kahle KT., Proc Natl Acad Sci U S A. February 17, 2004; 101 (7): 2064-9.
WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion. , Kahle KT., Nat Genet. December 1, 2003; 35 (4): 372-6.
WNK kinases regulate thiazide-sensitive Na-Cl cotransport. , Yang CL., J Clin Invest. April 1, 2003; 111 (7): 1039-45.