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Summary Anatomy Item Literature (1670) Expression Attributions Wiki
XB-ANAT-122

Papers associated with blood (and wnk4)

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Mutation affecting the conserved acidic WNK1 motif causes inherited hyperkalemic hyperchloremic acidosis., Louis-Dit-Picard H., J Clin Invest. December 1, 2020; 130 (12): 6379-6394.


WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4., Chávez-Canales M., Hypertension. November 1, 2014; 64 (5): 1047-53.


Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent process., Castañeda-Bueno M., Proc Natl Acad Sci U S A. May 15, 2012; 109 (20): 7929-34.


A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo., Oi K., Biol Open. February 15, 2012; 1 (2): 120-7.              


Rare mutations in SLC12A1 and SLC12A3 protect against hypertension by reducing the activity of renal salt cotransporters., Acuña R., J Hypertens. March 1, 2011; 29 (3): 475-83.


Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway., Rozansky DJ., J Clin Invest. September 1, 2009; 119 (9): 2601-12.


A novel protein kinase signaling pathway essential for blood pressure regulation in humans., Kahle KT., Trends Endocrinol Metab. April 1, 2008; 19 (3): 91-5.


Cotransporters, WNKs and hypertension: an update., Flatman PW., Curr Opin Nephrol Hypertens. March 1, 2008; 17 (2): 186-92.


WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis., Rinehart J., Proc Natl Acad Sci U S A. November 15, 2005; 102 (46): 16777-82.


WNK kinases and the control of blood pressure., Cope G., Pharmacol Ther. May 1, 2005; 106 (2): 221-31.


[WNK1 and WNK4, new players in salt and water homeostasis], Hadchouel J., Med Sci (Paris). January 1, 2005; 21 (1): 55-60.


WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia., Kahle KT., Proc Natl Acad Sci U S A. February 17, 2004; 101 (7): 2064-9.


WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion., Kahle KT., Nat Genet. December 1, 2003; 35 (4): 372-6.


WNK kinases regulate thiazide-sensitive Na-Cl cotransport., Yang CL., J Clin Invest. April 1, 2003; 111 (7): 1039-45.

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