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Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd. , Lee H , Lee H ., J Biol Chem. February 1, 2022; 298 (2): 101586.
Kindlin2 regulates neural crest specification via integrin-independent regulation of the FGF signaling pathway. , Wang H., Development. May 15, 2021; 148 (10):
Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis. , Lee H , Lee H ., Antioxidants (Basel). December 12, 2020; 9 (12):
WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis. , Nalesso G., Ann Rheum Dis. January 1, 2017; 76 (1): 218-226.
The Proto-oncogene Transcription Factor Ets1 Regulates Neural Crest Development through Histone Deacetylase 1 to Mediate Output of Bone Morphogenetic Protein Signaling. , Wang C ., J Biol Chem. September 4, 2015; 290 (36): 21925-38.
Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation. , Zhang X., Dev Cell. March 23, 2015; 32 (6): 719-30.
Temporal and spatial expression analysis of peripheral myelin protein 22 ( Pmp22) in developing Xenopus. , Tae HJ., Gene Expr Patterns. January 1, 2015; 17 (1): 26-30.
Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/ β-catenin signaling pathway. , Amado NG., J Biol Chem. December 19, 2014; 289 (51): 35456-67.
Smad1 transcription factor integrates BMP2 and Wnt3a signals in migrating cardiac progenitor cells. , Song J., Proc Natl Acad Sci U S A. May 20, 2014; 111 (20): 7337-42.
RAB8B is required for activity and caveolar endocytosis of LRP6. , Demir K., Cell Rep. September 26, 2013; 4 (6): 1224-34.
GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis-associated factors. , Leijten JC., Arthritis Res Ther. September 19, 2013; 15 (5): R126.
TBX3 Directs Cell-Fate Decision toward Mesendoderm. , Weidgang CE., Stem Cell Reports. August 29, 2013; 1 (3): 248-65.
Imparting regenerative capacity to limbs by progenitor cell transplantation. , Lin G ., Dev Cell. January 14, 2013; 24 (1): 41-51.
Signaling and transcriptional regulation in neural crest specification and migration: lessons from xenopus embryos. , Pegoraro C., Wiley Interdiscip Rev Dev Biol. January 1, 2013; 2 (2): 247-59.
Transient downregulation of Bmp signalling induces extra limbs in vertebrates. , Christen B ., Development. July 1, 2012; 139 (14): 2557-65.
Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation. , Zhang X., Cell. June 22, 2012; 149 (7): 1565-77.
WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways. , Nalesso G., J Cell Biol. May 2, 2011; 193 (3): 551-64.
Barhl2 limits growth of the diencephalic primordium through Caspase3 inhibition of beta-catenin activation. , Juraver-Geslin HA ., Proc Natl Acad Sci U S A. February 8, 2011; 108 (6): 2288-93.
Different requirement for Wnt/ β-catenin signaling in limb regeneration of larval and adult Xenopus. , Yokoyama H., PLoS One. January 1, 2011; 6 (7): e21721.
Involvement of p114-RhoGEF and Lfc in Wnt-3a- and dishevelled-induced RhoA activation and neurite retraction in N1E-115 mouse neuroblastoma cells. , Tsuji T., Mol Biol Cell. October 15, 2010; 21 (20): 3590-600.
Wnt/beta-catenin signaling is involved in the induction and maintenance of primitive hematopoiesis in the vertebrate embryo. , Tran HT., Proc Natl Acad Sci U S A. September 14, 2010; 107 (37): 16160-5.
Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction. , Wang Y., J Biol Chem. April 2, 2010; 285 (14): 10890-901.
Myosin-X is critical for migratory ability of Xenopus cranial neural crest cells. , Nie S ., Dev Biol. November 1, 2009; 335 (1): 132-42.
The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo. , Bryja V ., Mol Biol Cell. February 1, 2009; 20 (3): 924-36.
The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development. , Kazanskaya O., Development. November 1, 2008; 135 (22): 3655-64.
Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways. , Zhao H ., Development. April 1, 2008; 135 (7): 1283-93.
Noncanonical Wnt Signaling through G Protein-Linked PKCdelta Activation Promotes Bone Formation. , Tu X., Dev Cell. January 1, 2007; 12 (1): 113-27.
Shisa2 promotes the maturation of somitic precursors and transition to the segmental fate in Xenopus embryos. , Nagano T., Development. December 1, 2006; 133 (23): 4643-54.
Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. , Ellies DL., J Bone Miner Res. November 1, 2006; 21 (11): 1738-49.
NARF, an nemo-like kinase ( NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF). , Yamada M., J Biol Chem. July 28, 2006; 281 (30): 20749-20760.
Regulatory targets for transcription factor AP2 in Xenopus embryos. , Luo T., Dev Growth Differ. August 1, 2005; 47 (6): 403-13.
Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF. , Yamamoto A., Cell. January 28, 2005; 120 (2): 223-35.
Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes. , Gottardi CJ., J Cell Biol. October 25, 2004; 167 (2): 339-49.
R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis. , Kazanskaya O., Dev Cell. October 1, 2004; 7 (4): 525-34.
Murine Frizzled-1 behaves as an antagonist of the canonical Wnt/beta-catenin signaling. , Roman-Roman S., J Biol Chem. February 13, 2004; 279 (7): 5725-33.
Wnt proteins are lipid-modified and can act as stem cell growth factors. , Willert K., Nature. May 22, 2003; 423 (6938): 448-52.
Axis induction by wnt signaling: Target promoter responsiveness regulates competence. , Darken RS ., Dev Biol. June 1, 2001; 234 (1): 42-54.
Wnt antagonism initiates cardiogenesis in Xenopus laevis. , Schneider VA., Genes Dev. February 1, 2001; 15 (3): 304-15.
Analysis of the developing Xenopus tail bud reveals separate phases of gene expression during determination and outgrowth. , Beck CW ., Mech Dev. March 1, 1998; 72 (1-2): 41-52.