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Symmetrical Bispyridinium Compounds Act as Open Channel Blockers of Cation-Selective Ion Channels. , Haufe Y., ACS Pharmacol Transl Sci. March 8, 2024; 7 (3): 771-786.
Selective block of human Kv1.1 channels and an epilepsy-associated gain-of-function mutation by AETX-K peptide. , Zhao R., FASEB J. January 1, 2024; 38 (1): e23381.
Using Xenopus to discover new candidate genes involved in BOR and other congenital hearing loss syndromes. , Neal SJ., J Exp Zool B Mol Dev Evol. October 13, 2023;
Time-resolved quantitative proteomic analysis of the developing Xenopus otic vesicle reveals putative congenital hearing loss candidates. , Baxi AB., iScience. September 15, 2023; 26 (9): 107665.
Divergence between Hemichannel and Gap Junction Permeabilities of Connexin 30 and 26. , Xu J., Life (Basel). January 31, 2023; 13 (2):
Rack1 regulates cellular patterning and polarity in the mouse cochlea. , Yu D., Exp Cell Res. December 15, 2022; 421 (2): 113387.
Normal development in Xenopus laevis: A complementary staging table for the skull based on cartilage and bone. , MacKenzie EM., Dev Dyn. August 1, 2022; 251 (8): 1340-1356.
Morphometric study of the vestibuloauditory organ of the African clawed frog, Xenopus laevis. , Homma T., Anat Histol Embryol. July 1, 2022; 51 (4): 514-523.
Subtype-specific responses of hKv7.4 and hKv7.5 channels to polyunsaturated fatty acids reveal an unconventional modulatory site and mechanism. , Frampton DJA., Elife. June 1, 2022; 11
Vestibular Influence on Vertebrate Skeletal Symmetry and Body Shape. , Gordy C., Front Syst Neurosci. October 6, 2021; 15 753207.
Inhibition of the Aquaporin-1 Cation Conductance by Selected Furan Compounds Reduces Red Blood Cell Sickling. , Chow PH., Front Pharmacol. October 1, 2021; 12 794791.
The Allosteric Activation of α7 nAChR by α-Conotoxin MrIC Is Modified by Mutations at the Vestibular Site. , Gulsevin A., Toxins (Basel). August 10, 2021; 13 (8):
Using Xenopus to analyze neurocristopathies like Kabuki syndrome. , Schwenty-Lara J., Genesis. February 1, 2021; 59 (1-2): e23404.
Otic Neurogenesis in Xenopus laevis: Proliferation, Differentiation, and the Role of Eya1. , Almasoudi SH., Front Neuroanat. January 1, 2021; 15 722374.
Acute consequences of a unilateral VIIIth nerve transection on vestibulo-ocular and optokinetic reflexes in Xenopus laevis tadpoles. , Soupiadou P., J Neurol. December 1, 2020; 267 (Suppl 1): 62-75.
An In Vitro Study on Prestin Analog Gene in the Bullfrog Hearing Organs. , Wang Z., Neural Plast. July 2, 2020; 2020 3570732.
5-Hydroxymethyl-Furfural and Structurally Related Compounds Block the Ion Conductance in Human Aquaporin-1 Channels and Slow Cancer Cell Migration and Invasion. , Chow PH., Mol Pharmacol. July 1, 2020; 98 (1): 38-48.
Desensitization of NMDA channels requires ligand binding to both GluN1 and GluN2 subunits to constrict the pore beside the activation gate. , Chen YS ., J Neurochem. June 1, 2020; 153 (5): 549-566.
A lower X-gate in TASK channels traps inhibitors within the vestibule. , Rödström KEJ., Nature. June 1, 2020; 582 (7812): 443-447.
Tuning Scorpion Toxin Selectivity: Switching From KV1.1 to KV1.3. , Gigolaev AM., Front Pharmacol. April 7, 2020; 11 1010.
Six1 proteins with human branchio-oto-renal mutations differentially affect cranial gene expression and otic development. , Shah AM., Dis Model Mech. March 3, 2020; 13 (3):
Structural Determinants Mediating Tertiapin Block of Neuronal Kir3.2 Channels. , Patel D., Biochemistry. February 25, 2020; 59 (7): 836-850.
Stabilization of Gaze during Early Xenopus Development by Swimming-Related Utricular Signals. , Lambert FM ., Curr Biol. February 24, 2020; 30 (4): 746-753.e4.
Aquaporin-7: A Dynamic Aquaglyceroporin With Greater Water and Glycerol Permeability Than Its Bacterial Homolog GlpF. , Moss FJ., Front Physiol. January 1, 2020; 11 728.
Structural determinants underlying permeant discrimination of the Cx43 hemichannel. , Nielsen BS., J Biol Chem. November 8, 2019; 294 (45): 16789-16803.
Full-Length P2X7 Structures Reveal How Palmitoylation Prevents Channel Desensitization. , McCarthy AE., Cell. October 17, 2019; 179 (3): 659-670.e13.
Identification of Aethina tumida Kir Channels as Putative Targets of the Bee Venom Peptide Tertiapin Using Structure-Based Virtual Screening Methods. , Doupnik CA., Toxins (Basel). September 19, 2019; 11 (9):
Topologically correct central projections of tetrapod inner ear afferents require Fzd3. , Duncan JS., Sci Rep. July 16, 2019; 9 (1): 10298.
Trans-toxin ion-sensitivity of charybdotoxin-blocked potassium-channels reveals unbinding transitional states. , Moldenhauer H., Elife. July 4, 2019; 8
A Critical E-box in Barhl1 3' Enhancer Is Essential for Auditory Hair Cell Differentiation. , Hou K., Cells. May 15, 2019; 8 (5):
A valve-like mechanism controls desensitization of functional mammalian isoforms of acid-sensing ion channels. , Wu Y., Elife. May 2, 2019; 8
Mutations in the palm domain disrupt modulation of acid-sensing ion channel 1a currents by neuropeptides. , Bargeton B., Sci Rep. February 22, 2019; 9 (1): 2599.
Inhibitor binding mode and allosteric regulation of Na+-glucose symporters. , Bisignano P., Nat Commun. December 7, 2018; 9 (1): 5245.
Transplantation of Ears Provides Insights into Inner Ear Afferent Pathfinding Properties. , Gordy C., Dev Neurobiol. November 1, 2018; 78 (11): 1064-1080.
The degenerin region of the human bile acid-sensitive ion channel (BASIC) is involved in channel inhibition by calcium and activation by bile acids. , Ilyaskin AV., Pflugers Arch. July 1, 2018; 470 (7): 1087-1102.
Microvascular anatomy of the brain of the adult pipid frog, Xenopus laevis (Daudin): A scanning electron microscopic study of vascular corrosion casts. , Lametschwandtner A., J Morphol. July 1, 2018; 279 (7): 950-969.
Semicircular Canal Influences on the Developmental Tuning of the Translational Vestibulo-Ocular Reflex. , Branoner F., Front Neurol. June 5, 2018; 9 404.
Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation. , Zhang Z ., Elife. May 10, 2018; 7
The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels. , García IE., J Gen Physiol. May 7, 2018; 150 (5): 697-711.
High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics. , Mager T., Nat Commun. May 1, 2018; 9 (1): 1750.
Mechanism of NMDA receptor channel block by MK-801 and memantine. , Song X., Nature. April 1, 2018; 556 (7702): 515-519.
Sonic hedgehog antagonists reduce size and alter patterning of the frog inner ear. , Zarei S., Dev Neurobiol. December 1, 2017; 77 (12): 1385-1400.
Active site voltage clamp fluorometry of the sodium glucose cotransporter hSGLT1. , Gorraitz E., Proc Natl Acad Sci U S A. November 14, 2017; 114 (46): E9980-E9988.
Moving or being moved: that makes a difference. , Straka H ., J Neurol. October 1, 2017; 264 (Suppl 1): 28-33.
Modulation of the FMRFamide-gated Na+ channel by external Ca2. , Fujimoto A., Pflugers Arch. October 1, 2017; 469 (10): 1335-1347.
Expression and Purification of the Pain Receptor TRPV1 for Spectroscopic Analysis. , Velisetty P., Sci Rep. August 29, 2017; 7 (1): 9861.
no privacy, a Xenopus tropicalis mutant, is a model of human Hermansky-Pudlak Syndrome and allows visualization of internal organogenesis during tadpole development. , Nakayama T ., Dev Biol. June 15, 2017; 426 (2): 472-486.
Molecular Structure of the Human CFTR Ion Channel. , Liu F., Cell. March 23, 2017; 169 (1): 85-95.e8.
A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse. , Ulmer B., Sci Rep. February 21, 2017; 7 43010.
Spectrin βV adaptive mutations and changes in subcellular location correlate with emergence of hair cell electromotility in mammalians. , Cortese M., Proc Natl Acad Sci U S A. February 21, 2017; 114 (8): 2054-2059.