Papers associated with vestibule

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	Symmetrical Bispyridinium Compounds Act as Open Channel Blockers of Cation-Selective Ion Channels., Haufe Y., ACS Pharmacol Transl Sci. March 8, 2024; 7 (3): 771-786.
	Selective block of human Kv1.1 channels and an epilepsy-associated gain-of-function mutation by AETX-K peptide., Zhao R., FASEB J. January 1, 2024; 38 (1): e23381.
	Inhibition of the Aquaporin-1 Cation Conductance by Selected Furan Compounds Reduces Red Blood Cell Sickling., Chow PH., Front Pharmacol. October 1, 2021; 12 794791.
	The Allosteric Activation of α7 nAChR by α-Conotoxin MrIC Is Modified by Mutations at the Vestibular Site., Gulsevin A., Toxins (Basel). August 10, 2021; 13 (8):
	5-Hydroxymethyl-Furfural and Structurally Related Compounds Block the Ion Conductance in Human Aquaporin-1 Channels and Slow Cancer Cell Migration and Invasion., Chow PH., Mol Pharmacol. July 1, 2020; 98 (1): 38-48.
	Desensitization of NMDA channels requires ligand binding to both GluN1 and GluN2 subunits to constrict the pore beside the activation gate., Chen YS., J Neurochem. June 1, 2020; 153 (5): 549-566.
	A lower X-gate in TASK channels traps inhibitors within the vestibule., Rödström KEJ., Nature. June 1, 2020; 582 (7812): 443-447.
	Tuning Scorpion Toxin Selectivity: Switching From KV1.1 to KV1.3., Gigolaev AM., Front Pharmacol. April 7, 2020; 11 1010.
	Structural Determinants Mediating Tertiapin Block of Neuronal Kir3.2 Channels., Patel D., Biochemistry. February 25, 2020; 59 (7): 836-850.
	Aquaporin-7: A Dynamic Aquaglyceroporin With Greater Water and Glycerol Permeability Than Its Bacterial Homolog GlpF., Moss FJ., Front Physiol. January 1, 2020; 11 728.
	Structural determinants underlying permeant discrimination of the Cx43 hemichannel., Nielsen BS., J Biol Chem. November 8, 2019; 294 (45): 16789-16803.
	Full-Length P2X7 Structures Reveal How Palmitoylation Prevents Channel Desensitization., McCarthy AE., Cell. October 17, 2019; 179 (3): 659-670.e13.
	Identification of Aethina tumida Kir Channels as Putative Targets of the Bee Venom Peptide Tertiapin Using Structure-Based Virtual Screening Methods., Doupnik CA., Toxins (Basel). September 19, 2019; 11 (9):
	Trans-toxin ion-sensitivity of charybdotoxin-blocked potassium-channels reveals unbinding transitional states., Moldenhauer H., Elife. July 4, 2019; 8
	A valve-like mechanism controls desensitization of functional mammalian isoforms of acid-sensing ion channels., Wu Y., Elife. May 2, 2019; 8
	Mutations in the palm domain disrupt modulation of acid-sensing ion channel 1a currents by neuropeptides., Bargeton B., Sci Rep. February 22, 2019; 9 (1): 2599.
	Inhibitor binding mode and allosteric regulation of Na+-glucose symporters., Bisignano P., Nat Commun. December 7, 2018; 9 (1): 5245.
	The degenerin region of the human bile acid-sensitive ion channel (BASIC) is involved in channel inhibition by calcium and activation by bile acids., Ilyaskin AV., Pflugers Arch. July 1, 2018; 470 (7): 1087-1102.
	Microvascular anatomy of the brain of the adult pipid frog, Xenopus laevis (Daudin): A scanning electron microscopic study of vascular corrosion casts., Lametschwandtner A., J Morphol. July 1, 2018; 279 (7): 950-969.
	Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation., Zhang Z., Elife. May 10, 2018; 7
	Mechanism of NMDA receptor channel block by MK-801 and memantine., Song X., Nature. April 1, 2018; 556 (7702): 515-519.
	Active site voltage clamp fluorometry of the sodium glucose cotransporter hSGLT1., Gorraitz E., Proc Natl Acad Sci U S A. November 14, 2017; 114 (46): E9980-E9988.
	Modulation of the FMRFamide-gated Na+ channel by external Ca2., Fujimoto A., Pflugers Arch. October 1, 2017; 469 (10): 1335-1347.
	Expression and Purification of the Pain Receptor TRPV1 for Spectroscopic Analysis., Velisetty P., Sci Rep. August 29, 2017; 7 (1): 9861.
	Molecular Structure of the Human CFTR Ion Channel., Liu F., Cell. March 23, 2017; 169 (1): 85-95.e8.
	Structural determinants of NH3 and NH4+ transport by mouse Rhbg, a renal Rh glycoprotein., Abdulnour-Nakhoul S., Am J Physiol Renal Physiol. December 1, 2016; 311 (6): F1280-F1293.
	Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine., Nys M., Proc Natl Acad Sci U S A. October 25, 2016; 113 (43): E6696-E6703.
	Syndromic deafness mutations at Asn 14 differentially alter the open stability of Cx26 hemichannels., Sanchez HA., J Gen Physiol. July 1, 2016; 148 (1): 25-42.
	Critical Molecular Determinants of α7 Nicotinic Acetylcholine Receptor Allosteric Activation: SEPARATION OF DIRECT ALLOSTERIC ACTIVATION AND POSITIVE ALLOSTERIC MODULATION., Horenstein NA., J Biol Chem. March 4, 2016; 291 (10): 5049-67.
	The Ascaris suum nicotinic receptor, ACR-16, as a drug target: Four novel negative allosteric modulators from virtual screening., Zheng F., Int J Parasitol Drugs Drug Resist. February 10, 2016; 6 (1): 60-73.
	The Human Acid-Sensing Ion Channel ASIC1a: Evidence for a Homotetrameric Assembly State at the Cell Surface., van Bemmelen MX., PLoS One. August 4, 2015; 10 (8): e0135191.
	Pore dimensions and the role of occupancy in unitary conductance of Shaker K channels., Díaz-Franulic I., J Gen Physiol. August 1, 2015; 146 (2): 133-46.
	A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels., Napolitano LM., Proc Natl Acad Sci U S A. July 7, 2015; 112 (27): E3619-28.
	Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor., Spurny R., Proc Natl Acad Sci U S A. May 12, 2015; 112 (19): E2543-52.
	A Single Amino Acid Deletion (ΔF1502) in the S6 Segment of CaV2.1 Domain III Associated with Congenital Ataxia Increases Channel Activity and Promotes Ca2+ Influx., Bahamonde MI., PLoS One. January 1, 2015; 10 (12): e0146035.
	Tracking the molecular evolution of calcium permeability in a nicotinic acetylcholine receptor., Lipovsek M., Mol Biol Evol. December 1, 2014; 31 (12): 3250-65.
	Ion conduction and selectivity in acid-sensing ion channel 1., Yang L., J Gen Physiol. September 1, 2014; 144 (3): 245-55.
	Exploring the structure of the voltage-gated Na+ channel by an engineered drug access pathway to the receptor site for local anesthetics., Lukacs P., J Biol Chem. August 1, 2014; 289 (31): 21770-81.
	Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR., Cui G., J Gen Physiol. August 1, 2014; 144 (2): 159-79.
	NMDA receptor structures reveal subunit arrangement and pore architecture., Lee CH, Lee CH., Nature. July 10, 2014; 511 (7508): 191-7.
	Heme impairs the ball-and-chain inactivation of potassium channels., Sahoo N., Proc Natl Acad Sci U S A. October 15, 2013; 110 (42): E4036-44.
	Conformational changes in the lower palm domain of ASIC1a contribute to desensitization and RFamide modulation., Frey EN., PLoS One. August 12, 2013; 8 (8): e71733.
	Alkaline pH block of CLC-K kidney chloride channels mediated by a pore lysine residue., Gradogna A., Biophys J. July 2, 2013; 105 (1): 80-90.
	Implications of aberrant temperature-sensitive glucose transport via the glucose transporter deficiency mutant (GLUT1DS) T295M for the alternate-access and fixed-site transport models., Cunningham P., J Membr Biol. June 1, 2013; 246 (6): 495-511.
	Co-expression of Na(V)β subunits alters the kinetics of inhibition of voltage-gated sodium channels by pore-blocking μ-conotoxins., Zhang MM., Br J Pharmacol. April 1, 2013; 168 (7): 1597-610.
	Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels., Sauguet L., EMBO J. March 6, 2013; 32 (5): 728-41.
	Characterization of a ligand binding site in the human transient receptor potential ankyrin 1 pore., Klement G., Biophys J. February 19, 2013; 104 (4): 798-806.
	Conserved N-terminal negative charges support optimally efficient N-type inactivation of Kv1 channels., Prince A., PLoS One. January 1, 2013; 8 (4): e62695.
	A conserved pre-block interaction motif regulates potassium channel activation and N-type inactivation., Pfaffinger PJ., PLoS One. January 1, 2013; 8 (11): e79891.
	Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines., Spurny R., Proc Natl Acad Sci U S A. October 30, 2012; 109 (44): E3028-34.

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