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Summary Anatomy Item Literature (200) Expression Attributions Wiki
XB-ANAT-267

Papers associated with mouth primordium (and kcnh2)

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Marine algal toxin azaspiracid is an open-state blocker of hERG potassium channels., Twiner MJ., Chem Res Toxicol. September 17, 2012; 25 (9): 1975-84.


Recombinant expression of the toxic peptide ErgTx1 and role of Met35 on its stability and function., Jimenez-Vargas JM., Peptides. March 1, 2011; 32 (3): 560-7.


Probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243)., Xu X., Mol Pharmacol. June 1, 2008; 73 (6): 1709-21.


Probing the outer mouth structure of the HERG channel with peptide toxin footprinting and molecular modeling., Tseng GN., Biophys J. May 15, 2007; 92 (10): 3524-40.


[Electrophysiological characterization of long QT syndrome associated mutations V630A and N633S]., She HR., Zhonghua Xin Xue Guan Bing Za Zhi. June 1, 2006; 34 (6): 523-7.


Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels., Clarke CE., J Physiol. June 1, 2006; 573 (Pt 2): 291-304.


Structure-function studies of the outer mouth and voltage sensor domain of hERG., Tseng GN., Novartis Found Symp. January 1, 2005; 266 19-35; discussion 35-45.


Gating charges in the activation and inactivation processes of the HERG channel., Zhang M., J Gen Physiol. December 1, 2004; 124 (6): 703-18.                    


Structural and functional role of the extracellular s5-p linker in the HERG potassium channel., Liu J., J Gen Physiol. November 1, 2002; 120 (5): 723-37.                  


Use-dependent 'agonist' effect of azimilide on the HERG channel., Jiang M., J Pharmacol Exp Ther. December 1, 1999; 291 (3): 1324-36.


Effects of outer mouth mutations on hERG channel function: a comparison with similar mutations in the Shaker channel., Fan JS., Biophys J. June 1, 1999; 76 (6): 3128-40.


Regulation of deactivation by an amino terminal domain in human ether-à-go-go-related gene potassium channels., Wang J., J Gen Physiol. November 1, 1998; 112 (5): 637-47.              


Novel mechanism of HERG current suppression in LQT2: shift in voltage dependence of HERG inactivation., Nakajima T., Circ Res. August 24, 1998; 83 (4): 415-22.


Differential effects of bupivacaine on cardiac K channels: role of channel inactivation and subunit composition in drug-channel interaction., Lipka LJ., J Cardiovasc Electrophysiol. July 1, 1998; 9 (7): 727-42.


Modulation of HERG affinity for E-4031 by [K+]o and C-type inactivation., Wang S., FEBS Lett. November 3, 1997; 417 (1): 43-7.


Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel., Schönherr R., J Physiol. June 15, 1996; 493 ( Pt 3) 635-42.

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