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The NIMA-like kinase Nek2 is a key switch balancing cilia biogenesis and resorption in the development of left- right asymmetry. , Endicott SJ., Development. December 1, 2015; 142 (23): 4068-79.
Spindle-to-cortex communication in cleaving, polyspermic Xenopus eggs. , Field CM ., Mol Biol Cell. October 15, 2015; 26 (20): 3628-40.
Bimodal Interaction of Mammalian Polo-Like Kinase 1 and a Centrosomal Scaffold, Cep192, in the Regulation of Bipolar Spindle Formation. , Meng L., Mol Cell Biol. August 1, 2015; 35 (15): 2626-40.
Kif2a depletion generates chromosome segregation and pole coalescence defects in animal caps and inhibits gastrulation of the Xenopus embryo. , Eagleson G ., Mol Biol Cell. March 1, 2015; 26 (5): 924-37.
Microtubule nucleation remote from centrosomes may explain how asters span large cells. , Ishihara K., Proc Natl Acad Sci U S A. December 16, 2014; 111 (50): 17715-22.
The Cep192-organized aurora A- Plk1 cascade is essential for centrosome cycle and bipolar spindle assembly. , Joukov V., Mol Cell. August 21, 2014; 55 (4): 578-91.
The role of NEDD1 phosphorylation by Aurora A in chromosomal microtubule nucleation and spindle function. , Pinyol R., Curr Biol. January 21, 2013; 23 (2): 143-9.
Centrosomal protein of 192 kDa ( Cep192) promotes centrosome-driven spindle assembly by engaging in organelle-specific Aurora A activation. , Joukov V., Proc Natl Acad Sci U S A. December 7, 2010; 107 (49): 21022-7.
Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis. , Recino A., Biochem J. September 1, 2010; 430 (2): 207-13.
Phosphorylation of p53 is regulated by TPX2- Aurora A in xenopus oocytes. , Pascreau G., J Biol Chem. February 27, 2009; 284 (9): 5497-505.
Dissecting the role of Aurora A during spindle assembly. , Sardon T., EMBO J. October 8, 2008; 27 (19): 2567-79.
Localization of aurora A and aurora B kinases during interphase: role of the N-terminal domain. , Rannou Y., Cell Cycle. October 1, 2008; 7 (19): 3012-20.
Requirement of aurora-A kinase in astral microtubule polymerization and spindle microtubule flux. , Wang LH., Cell Cycle. April 15, 2008; 7 (8): 1104-11.
The BRCA1/ BARD1 heterodimer modulates ran-dependent mitotic spindle assembly. , Joukov V., Cell. November 3, 2006; 127 (3): 539-52.
Aurora A, mitotic entry, and spindle bipolarity. , Liu Q., Proc Natl Acad Sci U S A. April 11, 2006; 103 (15): 5811-6.
Aurora A kinase-coated beads function as microtubule-organizing centers and enhance RanGTP-induced spindle assembly. , Tsai MY., Curr Biol. December 6, 2005; 15 (23): 2156-63.
Aurora A activates D-TACC- Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules. , Barros TP., J Cell Biol. September 26, 2005; 170 (7): 1039-46.
Function and regulation of Maskin, a TACC family protein, in microtubule growth during mitosis. , Peset I., J Cell Biol. September 26, 2005; 170 (7): 1057-66.
Aurora A phosphorylation of TACC3/ maskin is required for centrosome-dependent microtubule assembly in mitosis. , Kinoshita K., J Cell Biol. September 26, 2005; 170 (7): 1047-55.
Overexpression of Aurora-A potentiates HRAS-mediated oncogenic transformation and is implicated in oral carcinogenesis. , Tatsuka M., Oncogene. February 3, 2005; 24 (6): 1122-7.
Searching for biomarkers of Aurora-A kinase activity: identification of in vitro substrates through a modified KESTREL approach. , Troiani S., J Proteome Res. January 1, 2005; 4 (4): 1296-303.
Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats. , Li JJ., Proc Natl Acad Sci U S A. December 28, 2004; 101 (52): 18123-8.
Overexpression of Aurora-A contributes to malignant development of human esophageal squamous cell carcinoma. , Tong T., Clin Cancer Res. November 1, 2004; 10 (21): 7304-10.
Amplification/overexpression of Aurora-A in human gastric carcinoma: potential role in differentiated type gastric carcinogenesis. , Kamada K., Oncol Rep. September 1, 2004; 12 (3): 593-9.
Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein. , Satinover DL., Proc Natl Acad Sci U S A. June 8, 2004; 101 (23): 8625-30.
Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition. , Dutertre S., J Cell Sci. May 15, 2004; 117 (Pt 12): 2523-31.
BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition. , Ouchi M., J Biol Chem. May 7, 2004; 279 (19): 19643-8.
Aurora-A kinase maintains the fidelity of early and late mitotic events in HeLa cells. , Marumoto T., J Biol Chem. December 19, 2003; 278 (51): 51786-95.
Identification of novel phosphorylation sites on Xenopus laevis Aurora A and analysis of phosphopeptide enrichment by immobilized metal-affinity chromatography. , Haydon CE., Mol Cell Proteomics. October 1, 2003; 2 (10): 1055-67.
Interaction of Aurora-A and centrosomin at the microtubule-nucleating site in Drosophila and mammalian cells. , Terada Y., J Cell Biol. September 1, 2003; 162 (5): 757-63.
Dynamic association of a tumor amplified kinase, Aurora-A, with the centrosome and mitotic spindle. , Stenoien DL., Cell Motil Cytoskeleton. June 1, 2003; 55 (2): 134-46.
Molecular dynamics of Aurora-A kinase in living mitotic cells simultaneously visualized with histone H3 and nuclear membrane protein importinalpha. , Sugimoto K., Cell Struct Funct. December 1, 2002; 27 (6): 457-67.
Aurora-A kinase interacting protein ( AIP), a novel negative regulator of human Aurora-A kinase. , Kiat LS., J Biol Chem. November 22, 2002; 277 (47): 45558-65.
Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis. , Goepfert TM., Cancer Res. July 15, 2002; 62 (14): 4115-22.
APC/Fizzy-Related targets Aurora-A kinase for proteolysis. , Castro A., EMBO Rep. May 1, 2002; 3 (5): 457-62.
Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis. , Berdnik D., Curr Biol. April 16, 2002; 12 (8): 640-7.
Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules. , Giet R., J Cell Biol. February 4, 2002; 156 (3): 437-51.
The non-catalytic domain of the Xenopus laevis auroraA kinase localises the protein to the centrosome. , Giet R., J Cell Sci. June 1, 2001; 114 (Pt 11): 2095-104.
The Xenopus laevis aurora/Ip11p-related kinase pEg2 participates in the stability of the bipolar mitotic spindle. , Giet R., Exp Cell Res. July 10, 2000; 258 (1): 145-51.
The Xenopus laevis centrosome aurora/ Ipl1-related kinase. , Giet R., Biol Cell. July 1, 1999; 91 (6): 461-70.
Cell cycle-dependent expression and centrosome localization of a third human aurora/ Ipl1-related protein kinase, AIK3. , Kimura M., J Biol Chem. March 12, 1999; 274 (11): 7334-40.
A method for in situ mitotic spindle binding assay. , Giet R., Exp Cell Res. November 1, 1998; 244 (2): 470-3.
The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly. , Roghi C., J Cell Sci. March 1, 1998; 111 ( Pt 5) 557-72.
Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1. , Kimura M., J Biol Chem. May 23, 1997; 272 (21): 13766-71.