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Nuclei determine the spatial origin of mitotic waves. , Nolet FE., Elife. May 26, 2020; 9
Kif2a Scales Meiotic Spindle Size in Hymenochirus boettgeri. , Miller KE., Curr Biol. November 4, 2019; 29 (21): 3720-3727.e5.
Kinesin-5 Promotes Microtubule Nucleation and Assembly by Stabilizing a Lattice-Competent Conformation of Tubulin. , Chen GY., Curr Biol. July 22, 2019; 29 (14): 2259-2269.e4.
Induction of a Spindle-Assembly-Competent M Phase in Xenopus Egg Extracts. , Bisht JS., Curr Biol. April 22, 2019; 29 (8): 1273-1285.e5.
Highly efficient photocontrol of mitotic kinesin Eg5 ATPase activity using a novel photochromic compound composed of two azobenzene derivatives. , Sadakane K., J Biochem. October 1, 2018; 164 (4): 295-301.
Structural analysis of the role of TPX2 in branching microtubule nucleation. , Alfaro-Aco R., J Cell Biol. April 3, 2017; 216 (4): 983-997.
Mechanical properties of spindle poles are symmetrically balanced. , Suzuki K., Biophys Physicobiol. January 24, 2017; 14 1-11.
The Kinesin-5 Chemomechanical Cycle Is Dominated by a Two-heads-bound State. , Chen GY., J Biol Chem. September 23, 2016; 291 (39): 20283-20294.
The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery. , Toriyama M., Nat Genet. June 1, 2016; 48 (6): 648-56.
Phosphorylation of targeting protein for Xenopus kinesin-like protein 2 ( TPX2) at threonine 72 in spindle assembly. , Shim SY ., J Biol Chem. April 3, 2015; 290 (14): 9122-34.
Dynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesion. , Jones LA., J Cell Biol. November 24, 2014; 207 (4): 499-516.
Spatial organization of cytokinesis signaling reconstituted in a cell-free system. , Nguyen PA., Science. October 10, 2014; 346 (6206): 244-7.
TPX2 levels modulate meiotic spindle size and architecture in Xenopus egg extracts. , Helmke KJ., J Cell Biol. August 4, 2014; 206 (3): 385-93.
Developmental expression and role of Kinesin Eg5 during Xenopus laevis embryogenesis. , Fernández JP., Dev Dyn. April 1, 2014; 243 (4): 527-40.
Self-organization of stabilized microtubules by both spindle and midzone mechanisms in Xenopus egg cytosol. , Mitchison TJ ., Mol Biol Cell. May 1, 2013; 24 (10): 1559-73.
Microtubule redistribution in growth cones elicited by focal inactivation of kinesin-5. , Nadar VC., J Neurosci. April 25, 2012; 32 (17): 5783-94.
Breaking the ties that bind: new advances in centrosome biology. , Mardin BR., J Cell Biol. April 2, 2012; 197 (1): 11-8.
Alzheimer Aβ disrupts the mitotic spindle and directly inhibits mitotic microtubule motors. , Borysov SI., Cell Cycle. May 1, 2011; 10 (9): 1397-410.
Lamin B counteracts the kinesin Eg5 to restrain spindle pole separation during spindle assembly. , Goodman B., J Biol Chem. November 5, 2010; 285 (45): 35238-44.
Microtubule organization by the antagonistic mitotic motors kinesin-5 and kinesin-14. , Hentrich C., J Cell Biol. May 3, 2010; 189 (3): 465-80.
The ATPase cycle of the mitotic motor CENP-E. , Rosenfeld SS., J Biol Chem. November 20, 2009; 284 (47): 32858-68.
Spindle fusion requires dynein-mediated sliding of oppositely oriented microtubules. , Gatlin JC ., Curr Biol. February 24, 2009; 19 (4): 287-96.
Multiple kinesin motors coordinate cytoplasmic RNA transport on a subpopulation of microtubules in Xenopus oocytes. , Messitt TJ., Dev Cell. September 1, 2008; 15 (3): 426-436.
Poleward transport of Eg5 by dynein-dynactin in Xenopus laevis egg extract spindles. , Uteng M., J Cell Biol. August 25, 2008; 182 (4): 715-26.
Microtubule cross-linking triggers the directional motility of kinesin-5. , Kapitein LC., J Cell Biol. August 11, 2008; 182 (3): 421-8.
Single-headed mode of kinesin-5. , Kaseda K., EMBO Rep. August 1, 2008; 9 (8): 761-5.
Spindle pole regulation by a discrete Eg5-interacting domain in TPX2. , Eckerdt F., Curr Biol. April 8, 2008; 18 (7): 519-25.
Phosphorylation by Cdk1 increases the binding of Eg5 to microtubules in vitro and in Xenopus egg extract spindles. , Cahu J., PLoS One. January 1, 2008; 3 (12): e3936.
Bod1, a novel kinetochore protein required for chromosome biorientation. , Porter IM., J Cell Biol. October 22, 2007; 179 (2): 187-97.
Load-dependent release limits the processive stepping of the tetrameric Eg5 motor. , Korneev MJ., Eur Biophys J. July 1, 2007; 36 (6): 675-81.
Allosteric inhibition of kinesin-5 modulates its processive directional motility. , Kwok BH., Nat Chem Biol. September 1, 2006; 2 (9): 480-5.
Biophysical model of self-organized spindle formation patterns without centrosomes and kinetochores. , Schaffner SC., Proc Natl Acad Sci U S A. July 25, 2006; 103 (30): 11166-71.
Deciphering protein function during mitosis in PtK cells using RNAi. , Stout JR., BMC Cell Biol. January 19, 2006; 7 26.
Synthesis and biological evaluation of new tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin Eg5. , Sunder-Plassmann N., Bioorg Med Chem. November 15, 2005; 13 (22): 6094-111.
Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles. , Mitchison TJ ., Mol Biol Cell. June 1, 2005; 16 (6): 3064-76.
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks. , Kapitein LC., Nature. May 5, 2005; 435 (7038): 114-8.
Mechanism of inhibition of human KSP by monastrol: insights from kinetic analysis and the effect of ionic strength on KSP inhibition. , Luo L., Biochemistry. December 7, 2004; 43 (48): 15258-66.
The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles. , Miyamoto DT., J Cell Biol. December 6, 2004; 167 (5): 813-8.
Eg5 causes elongation of meiotic spindles when flux-associated microtubule depolymerization is blocked. , Shirasu-Hiza M., Curr Biol. November 9, 2004; 14 (21): 1941-5.
The rate of bipolar spindle assembly depends on the microtubule-gliding velocity of the mitotic kinesin Eg5. , Kwok BH., Curr Biol. October 5, 2004; 14 (19): 1783-8.
Mammalian RanBP1 regulates centrosome cohesion during mitosis. , Di Fiore B., J Cell Sci. August 15, 2003; 116 (Pt 16): 3399-411.
A novel action of terpendole E on the motor activity of mitotic Kinesin Eg5. , Nakazawa J., Chem Biol. February 1, 2003; 10 (2): 131-7.
hTPX2 is required for normal spindle morphology and centrosome integrity during vertebrate cell division. , Garrett S., Curr Biol. December 10, 2002; 12 (23): 2055-9.
Reorganization of the microtubule array in prophase/prometaphase requires cytoplasmic dynein-dependent microtubule transport. , Rusan NM., J Cell Biol. September 16, 2002; 158 (6): 997-1003.
Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5. , Maliga Z., Chem Biol. September 1, 2002; 9 (9): 989-96.
Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix. , Kapoor TM., J Cell Biol. September 17, 2001; 154 (6): 1125-33.
Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker. , Turner J., J Biol Chem. July 6, 2001; 276 (27): 25496-502.
Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities. , Wilde A., Nat Cell Biol. March 1, 2001; 3 (3): 221-7.
Structural comparison of dimeric Eg5, Neurospora kinesin (Nkin) and Ncd head-Nkin neck chimera with conventional kinesin. , Hirose K., EMBO J. October 16, 2000; 19 (20): 5308-14.
Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5. , Kapoor TM., J Cell Biol. September 4, 2000; 150 (5): 975-88.