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R-Spondin 2 governs Xenopus left- right body axis formation by establishing an FGF signaling gradient. , Lee H , Lee H ., Nat Commun. February 2, 2024; 15 (1): 1003.
ZSWIM4 regulates embryonic patterning and BMP signaling by promoting nuclear Smad1 degradation. , Wang C ., EMBO Rep. February 1, 2024; 25 (2): 646-671.
Addition of exogenous diacylglycerol enhances Wnt/β-catenin signaling through stimulation of macropinocytosis. , Azbazdar Y., iScience. October 20, 2023; 26 (10): 108075.
The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling. , Ng VH., Nat Commun. October 5, 2023; 14 (1): 6173.
Thyroid hormone receptor knockout prevents the loss of Xenopus tail regeneration capacity at metamorphic climax. , Wang S., Cell Biosci. February 23, 2023; 13 (1): 40.
Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd. , Lee H , Lee H ., J Biol Chem. February 1, 2022; 298 (2): 101586.
Analysis of the Expression Pattern of Cajal-Retzius Cell Markers in the Xenopus laevis Forebrain. , Jiménez S., Brain Behav Evol. January 1, 2022; 96 (4-6): 263-282.
Rab7 is required for mesoderm patterning and gastrulation in Xenopus. , Kreis J., Biol Open. July 15, 2021; 10 (7):
Secreted inhibitors drive the loss of regeneration competence in Xenopus limbs. , Aztekin C ., Development. June 1, 2021; 148 (11):
Kindlin2 regulates neural crest specification via integrin-independent regulation of the FGF signaling pathway. , Wang H., Development. May 15, 2021; 148 (10):
Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis. , Lee H , Lee H ., Antioxidants (Basel). December 12, 2020; 9 (12):
R-spondins are BMP receptor antagonists in Xenopus early embryonic development. , Lee H , Lee H ., Nat Commun. November 4, 2020; 11 (1): 5570.
TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis. , Chen M., Elife. September 14, 2020; 9
The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer. , Chang LS., Elife. January 14, 2020; 9
Pinhead signaling regulates mesoderm heterogeneity via FGF receptor-dependent pathway. , Ossipova O., Development. January 1, 2020;
The Chalcone Lonchocarpin Inhibits Wnt/ β-Catenin Signaling and Suppresses Colorectal Cancer Proliferation. , Predes D., Cancers (Basel). December 7, 2019; 11 (12):
Non-acylated Wnts Can Promote Signaling. , Speer KF., Cell Rep. January 22, 2019; 26 (4): 875-883.e5.
Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis. , Ding Y ., Proc Natl Acad Sci U S A. September 25, 2018; 115 (39): E9135-E9144.
Regulation of neural crest development by the formin family protein Daam1. , Ossipova O., Genesis. June 1, 2018; 56 (6-7): e23108.
Timing is everything: Reiterative Wnt, BMP and RA signaling regulate developmental competence during endoderm organogenesis. , Rankin SA , Rankin SA ., Dev Biol. February 1, 2018; 434 (1): 121-132.
A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates. , Plouhinec JL., PLoS Biol. October 19, 2017; 15 (10): e2004045.
Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. , Kirsch N., Dev Cell. October 9, 2017; 43 (1): 71-82.e6.
The phosphatase Pgam5 antagonizes Wnt/ β-Catenin signaling in embryonic anterior- posterior axis patterning. , Rauschenberger V., Development. June 15, 2017; 144 (12): 2234-2247.
PTK7 localization and protein stability is affected by canonical Wnt ligands. , Berger H., J Cell Sci. June 1, 2017; 130 (11): 1890-1903.
FoxD1 protein interacts with Wnt and BMP signaling to differentially pattern mesoderm and neural tissue. , Polevoy H., Int J Dev Biol. January 1, 2017; 61 (3-4-5): 293-302.
An Evolutionarily Conserved Network Mediates Development of the zona limitans intrathalamica, a Sonic Hedgehog-Secreting Caudal Forebrain Signaling Center. , Sena E., J Dev Biol. October 20, 2016; 4 (4):
Wnt proteins can direct planar cell polarity in vertebrate ectoderm. , Chu CW., Elife. September 23, 2016; 5
The polycystin complex mediates Wnt/Ca(2+) signalling. , Kim S., Nat Cell Biol. July 1, 2016; 18 (7): 752-764.
Lens regeneration from the cornea requires suppression of Wnt/ β-catenin signaling. , Hamilton PW., Exp Eye Res. April 1, 2016; 145 206-215.
A novel role for the tumour suppressor Nitrilase1 modulating the Wnt/ β-catenin signalling pathway. , Mittag S., Cell Discov. January 5, 2016; 2 15039.
Genes regulated by potassium channel tetramerization domain containing 15 (Kctd15) in the developing neural crest. , Wong TC., Int J Dev Biol. January 1, 2016; 60 (4-6): 159-66.
Novel β-carbolines against colorectal cancer cell growth via inhibition of Wnt/ β-catenin signaling. , Li X., Cell Death Discov. October 5, 2015; 1 15033.
The Proto-oncogene Transcription Factor Ets1 Regulates Neural Crest Development through Histone Deacetylase 1 to Mediate Output of Bone Morphogenetic Protein Signaling. , Wang C ., J Biol Chem. September 4, 2015; 290 (36): 21925-38.
Kdm2a/b Lysine Demethylases Regulate Canonical Wnt Signaling by Modulating the Stability of Nuclear β-Catenin. , Lu L., Dev Cell. June 22, 2015; 33 (6): 660-74.
Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation. , Zhang X., Dev Cell. March 23, 2015; 32 (6): 719-30.
The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation. , Acosta H., Development. March 15, 2015; 142 (6): 1146-58.
The requirement of histone modification by PRDM12 and Kdm4a for the development of pre-placodal ectoderm and neural crest in Xenopus. , Matsukawa S ., Dev Biol. March 1, 2015; 399 (1): 164-176.
Prepatterning and patterning of the thalamus along embryonic development of Xenopus laevis. , Bandín S., Front Neuroanat. February 3, 2015; 9 107.
Early development of the neural plate: new roles for apoptosis and for one of its main effectors caspase-3. , Juraver-Geslin HA ., Genesis. February 1, 2015; 53 (2): 203-24.
Development of the vertebrate tailbud. , Beck CW ., Wiley Interdiscip Rev Dev Biol. January 1, 2015; 4 (1): 33-44.
Temporal and spatial expression analysis of peripheral myelin protein 22 ( Pmp22) in developing Xenopus. , Tae HJ., Gene Expr Patterns. January 1, 2015; 17 (1): 26-30.
Direct regulation of siamois by VegT is required for axis formation in Xenopus embryo. , Li HY., Int J Dev Biol. January 1, 2015; 59 (10-12): 443-51.
Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/ β-catenin signaling pathway. , Amado NG., J Biol Chem. December 19, 2014; 289 (51): 35456-67.
Fezf2 promotes neuronal differentiation through localised activation of Wnt/ β-catenin signalling during forebrain development. , Zhang S ., Development. December 1, 2014; 141 (24): 4794-805.
Embryological manipulations in the developing Xenopus inner ear reveal an intrinsic role for Wnt signaling in dorsal- ventral patterning. , Forristall CA ., Dev Dyn. October 1, 2014; 243 (10): 1262-74.
Custos controls β-catenin to regulate head development during vertebrate embryogenesis. , Komiya Y., Proc Natl Acad Sci U S A. September 9, 2014; 111 (36): 13099-104.
The roles of Frizzled-3 and Wnt3a on melanocyte development: in vitro studies on neural crest cells and melanocyte precursor cell lines. , Chang CH ., J Dermatol Sci. August 1, 2014; 75 (2): 100-8.
PTK7 modulates Wnt signaling activity via LRP6. , Bin-Nun N., Development. January 1, 2014; 141 (2): 410-21.
A secreted splice variant of the Xenopus frizzled-4 receptor is a biphasic modulator of Wnt signalling. , Gorny AK., Cell Commun Signal. November 19, 2013; 11 89.
RAB8B is required for activity and caveolar endocytosis of LRP6. , Demir K., Cell Rep. September 26, 2013; 4 (6): 1224-34.