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A revised mechanism of action of hyperaldosteronism-linked mutations in cytosolic domains of GIRK4 (KCNJ5). , Shalomov B., J Physiol. March 1, 2022; 600 (6): 1419-1437.
AsKC11, a Kunitz Peptide from Anemonia sulcata, Is a Novel Activator of G Protein-Coupled Inward-Rectifier Potassium Channels. , An D., Mar Drugs. February 15, 2022; 20 (2):
A novel ion conducting route besides the central pore in an inherited mutant of G-protein-gated inwardly rectifying K+ channel. , Chen IS., J Physiol. February 1, 2022; 600 (3): 603-622.
Voltage dependence of the cannabinoid CB1 receptor. , Goldberger E., Front Pharmacol. January 1, 2022; 13 1022275.
Consequences of somatic mutations of GIRK1 detected in primary malign tumors on expression and function of G-protein activated, inwardly rectifying, K+ channels. , Pelzmann B., Front Oncol. January 1, 2022; 12 998907.
WIN55,212-2, a Dual Modulator of Cannabinoid Receptors and G Protein-Coupled Inward Rectifier Potassium Channels. , An D., Biomedicines. April 28, 2021; 9 (5):
A Collision Coupling Model Governs the Activation of Neuronal GIRK1/2 Channels by Muscarinic-2 Receptors. , Berlin S., Front Pharmacol. April 7, 2020; 11 1216.
The small molecule GAT1508 activates brain-specific GIRK1/2 channel heteromers and facilitates conditioned fear extinction in rodents. , Xu Y ., J Biol Chem. March 13, 2020; 295 (11): 3614-3634.
Mutant KCNJ3 and KCNJ5 Potassium Channels as Novel Molecular Targets in Bradyarrhythmias and Atrial Fibrillation. , Yamada N., Circulation. April 30, 2019; 139 (18): 2157-2169.
Familial Sinus Node Disease Caused by a Gain of GIRK (G-Protein Activated Inwardly Rectifying K+ Channel) Channel Function. , Kuß J., Circ Genom Precis Med. January 1, 2019; 12 (1): e002238.
A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction. , Stallmeyer B., Circ Res. May 12, 2017; 120 (10): e33-e44.
Cholesterol up-regulates neuronal G protein-gated inwardly rectifying potassium (GIRK) channel activity in the hippocampus. , Bukiya AN., J Biol Chem. April 14, 2017; 292 (15): 6135-6147.
Baclofen and other GABAB receptor agents are allosteric modulators of the CXCL12 chemokine receptor CXCR4. , Guyon A., J Neurosci. July 10, 2013; 33 (28): 11643-54.
The polarization of the G-protein activated potassium channel GIRK5 to the vegetal pole of Xenopus laevis oocytes is driven by a di-leucine motif. , Díaz-Bello B., PLoS One. May 15, 2013; 8 (5): e64096.
Crystal structure of the mammalian GIRK2 K+ channel and gating regulation by G proteins, PIP2, and sodium. , Whorton MR., Cell. September 30, 2011; 147 (1): 199-208.
Inhibition of g protein-activated inwardly rectifying k channels by phencyclidine. , Kobayashi T., Curr Neuropharmacol. March 1, 2011; 9 (1): 244-6.
Four and a half LIM protein 1C (FHL1C): a binding partner for voltage-gated potassium channel K( v1.5). , Poparic I., PLoS One. January 1, 2011; 6 (10): e26524.
Inhibition of G protein-activated inwardly rectifying K+ channels by different classes of antidepressants. , Kobayashi T., PLoS One. January 1, 2011; 6 (12): e28208.
Gating of a G protein-sensitive mammalian Kir3.1 prokaryotic Kir channel chimera in planar lipid bilayers. , Leal-Pinto E., J Biol Chem. December 17, 2010; 285 (51): 39790-800.
Intron 4 containing novel GABAB1 isoforms impair GABAB receptor function. , Lee C , Lee C ., PLoS One. November 16, 2010; 5 (11): e14044.
Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective norepinephrine reuptake inhibitors atomoxetine and reboxetine. , Kobayashi T., Neuropsychopharmacology. June 1, 2010; 35 (7): 1560-9.
Pregnenolone sulfate potentiates the inwardly rectifying K channel Kir2.3. , Kobayashi T., PLoS One. July 21, 2009; 4 (7): e6311.
Inhibitory effects of the antiepileptic drug ethosuximide on G protein-activated inwardly rectifying K+ channels. , Kobayashi T., Neuropharmacology. February 1, 2009; 56 (2): 499-506.
Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit. , Calloe K., Biochem Biophys Res Commun. December 28, 2007; 364 (4): 889-95.
Inhibition by cocaine of G protein-activated inwardly rectifying K+ channels expressed in Xenopus oocytes. , Kobayashi T., Toxicol In Vitro. June 1, 2007; 21 (4): 656-64.
Galphai3 primes the G protein-activated K+ channels for activation by coexpressed Gbetagamma in intact Xenopus oocytes. , Rubinstein M., J Physiol. May 15, 2007; 581 (Pt 1): 17-32.
Inhibitory effect of gabapentin on N-methyl-D-aspartate receptors expressed in Xenopus oocytes. , Hara K., Acta Anaesthesiol Scand. January 1, 2007; 51 (1): 122-8.
The GIRK1 brain variant GIRK1d and its functional impact on heteromultimeric GIRK channels. , Steinecker B., J Recept Signal Transduct Res. January 1, 2007; 27 (5-6): 369-82.
RGS3 and RGS4 differentially associate with G protein-coupled receptor-Kir3 channel signaling complexes revealing two modes of RGS modulation. Precoupling and collision coupling. , Jaén C., J Biol Chem. November 10, 2006; 281 (45): 34549-60.
Inhibition of G protein-activated inwardly rectifying K+ channels by the antidepressant paroxetine. , Kobayashi T., J Pharmacol Sci. November 1, 2006; 102 (3): 278-87.
Inhibition of G protein-activated inwardly rectifying K+ channels by ifenprodil. , Kobayashi T., Neuropsychopharmacology. March 1, 2006; 31 (3): 516-24.
Tyrosine phosphorylation of K(ir)3.1 in spinal cord is induced by acute inflammation, chronic neuropathic pain, and behavioral stress. , Ippolito DL., J Biol Chem. December 16, 2005; 280 (50): 41683-93.
Mutation of critical GIRK subunit residues disrupts N- and C-termini association and channel function. , Sarac R., J Neurosci. February 16, 2005; 25 (7): 1836-46.
Molecular cloning and characterization of a new RGS protein of Medaka. , Itoh M., Gene. January 31, 2005; 345 (2): 165-71.
RFamide-related peptides signal through the neuropeptide FF receptor and regulate pain-related responses in the rat. , Pertovaara A., Neuroscience. January 1, 2005; 134 (3): 1023-32.
Modulators of G protein-activated inwardly rectifying K+ channels: potentially therapeutic agents for addictive drug users. , Kobayashi T., Ann N Y Acad Sci. October 1, 2004; 1025 590-4.
Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs. , Kobayashi T., Neuropsychopharmacology. October 1, 2004; 29 (10): 1841-51.
A retinal-specific regulator of G-protein signaling interacts with Galpha(o) and accelerates an expressed metabotropic glutamate receptor 6 cascade. , Dhingra A., J Neurosci. June 23, 2004; 24 (25): 5684-93.
Inhibition of G protein-activated inwardly rectifying K+ channels by fluoxetine (Prozac). , Kobayashi T., Br J Pharmacol. March 1, 2003; 138 (6): 1119-28.
Single channel analysis of the regulation of GIRK1/ GIRK4 channels by protein phosphorylation. , Müllner D., Biophys J. February 1, 2003; 84 (2 Pt 1): 1399-409.
Early embryonic expression of ion channels and pumps in chick and Xenopus development. , Rutenberg J., Dev Dyn. December 1, 2002; 225 (4): 469-84.
LB50053: a 5-hydroxytrypamine(1a) agent with a high binding affinity and a potency evoking a K(+) current. , Kim HS ., Pharmacology. August 1, 2002; 65 (4): 175-81.
Functional expression of a novel ginsenoside Rf binding protein from rat brain mRNA in Xenopus laevis oocytes. , Choi S., Mol Pharmacol. April 1, 2002; 61 (4): 928-35.
Does acetaldehyde mediate ethanol action in the central nervous system? , Mascia MP., Alcohol Clin Exp Res. November 1, 2001; 25 (11): 1570-5.
Yeast screen for constitutively active mutant G protein-activated potassium channels. , Yi BA., Neuron. March 1, 2001; 29 (3): 657-67.
Cloning and characterization of G protein-gated inward rectifier K+ channel ( GIRK1) isoforms from heart and brain. , Zhu L., J Mol Neurosci. February 1, 2001; 16 (1): 21-32.
G-protein mediated gating of inward-rectifier K+ channels. , Mark MD., Eur J Biochem. October 1, 2000; 267 (19): 5830-6.
TrkB activation by brain-derived neurotrophic factor inhibits the G protein-gated inward rectifier Kir3 by tyrosine phosphorylation of the channel. , Rogalski SL., J Biol Chem. August 18, 2000; 275 (33): 25082-8.
Inhibition by various antipsychotic drugs of the G-protein-activated inwardly rectifying K(+) ( GIRK) channels expressed in xenopus oocytes. , Kobayashi T., Br J Pharmacol. April 1, 2000; 129 (8): 1716-22.
Kir3.1/3.2 encodes an I(KACh)-like current in gastrointestinal myocytes. , Bradley KK., Am J Physiol Gastrointest Liver Physiol. February 1, 2000; 278 (2): G289-96.