???pagination.result.count???
TopBP1 utilises a bipartite GINS binding mode to support genome replication. , Day M., Nat Commun. February 27, 2024; 15 (1): 1797.
The structural mechanism of dimeric DONSON in replicative helicase activation. , Cvetkovic MA., Mol Cell. November 16, 2023; 83 (22): 4017-4031.e9.
DONSON facilitates Cdc45 and GINS chromatin association and is essential for DNA replication initiation. , Kingsley G., Nucleic Acids Res. October 13, 2023; 51 (18): 9748-9763.
Rif1 restrains the rate of replication origin firing in Xenopus laevis. , Haccard O ., Commun Biol. July 29, 2023; 6 (1): 788.
RTEL1 and MCM10 overcome topological stress during vertebrate replication termination. , Campos LV., Cell Rep. February 28, 2023; 42 (2): 112109.
The p97 segregase cofactor Ubxn7 facilitates replisome disassembly during S-phase. , Tarcan Z., J Biol Chem. August 1, 2022; 298 (8): 102234.
The HMCES DNA-protein cross-link functions as an intermediate in DNA interstrand cross-link repair. , Semlow DR., Nat Struct Mol Biol. May 1, 2022; 29 (5): 451-462.
Polo-like kinase 1 (Plk1) regulates DNA replication origin firing and interacts with Rif1 in Xenopus. , Ciardo D., Nucleic Acids Res. September 27, 2021; 49 (17): 9851-9869.
Multistep mechanism of G-quadruplex resolution during DNA replication. , Sato K ., Sci Adv. September 24, 2021; 7 (39): eabf8653.
The DNA replication fork suppresses CMG unloading from chromatin before termination. , Low E., Genes Dev. November 1, 2020; 34 (21-22): 1534-1545.
Topoisomerase II Is Crucial for Fork Convergence during Vertebrate Replication Termination. , Heintzman DR., Cell Rep. October 8, 2019; 29 (2): 422-436.e5.
Mitotic replisome disassembly depends on TRAIP ubiquitin ligase activity. , Priego Moreno S., Life Sci Alliance. April 12, 2019; 2 (2):
RPA-coated single-stranded DNA promotes the ETAA1-dependent activation of ATR. , Lyu K., Cell Cycle. April 1, 2019; 18 (8): 898-913.
Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements. , Deng L., Mol Cell. March 7, 2019; 73 (5): 915-929.e6.
TRAIP is a master regulator of DNA interstrand crosslink repair. , Wu RA., Nature. March 1, 2019; 567 (7747): 267-272.
Mitotic entry drives replisome disassembly at stalled replication forks. , Hashimoto Y., Biochem Biophys Res Commun. November 17, 2018; 506 (1): 108-113.
Replication Fork Reversal during DNA Interstrand Crosslink Repair Requires CMG Unloading. , Amunugama R., Cell Rep. June 19, 2018; 23 (12): 3419-3428.
Suppression of targeting of Dbf4-dependent kinase to pre-replicative complex in G0 nuclei. , Okada T., Genes Cells. February 1, 2018; 23 (2): 94-104.
MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication. , Kumagai A ., Mol Biol Cell. November 1, 2017; 28 (22): 2998-3012.
Reversal of DDK-Mediated MCM Phosphorylation by Rif1- PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/ Chk1. , Alver RC., Cell Rep. March 7, 2017; 18 (10): 2508-2520.
Xenopus Mcm10 is a CDK-substrate required for replication fork stability. , Chadha GS., Cell Cycle. August 17, 2016; 15 (16): 2183-2195.
Structure of human Cdc45 and implications for CMG helicase function. , Simon AC., Nat Commun. May 18, 2016; 7 11638.
Studying essential DNA metabolism proteins in Xenopus egg extract. , Sannino V., Int J Dev Biol. January 1, 2016; 60 (7-8-9): 221-227.
The mechanism of DNA replication termination in vertebrates. , Dewar JM ., Nature. September 17, 2015; 525 (7569): 345-50.
DNA interstrand cross-link repair requires replication-fork convergence. , Zhang J., Nat Struct Mol Biol. March 1, 2015; 22 (3): 242-7.
RecQ4 promotes the conversion of the pre-initiation complex at a site-specific origin for DNA unwinding in Xenopus egg extracts. , Sanuki Y., Cell Cycle. January 1, 2015; 14 (7): 1010-23.
Protein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiation. , Gao Y., J Biol Chem. December 26, 2014; 289 (52): 35987-6000.
NCOA4 transcriptional coactivator inhibits activation of DNA replication origins. , Bellelli R., Mol Cell. July 3, 2014; 55 (1): 123-37.
Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1. , Poh WT., Open Biol. January 8, 2014; 4 (1): 130138.
Mta2 promotes Tipin-dependent maintenance of replication fork integrity. , Errico A., Cell Cycle. January 1, 2014; 13 (13): 2120-8.
Depletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts. , Taylor EM., Nucleic Acids Res. September 1, 2013; 41 (16): 7725-37.
DNA topoisomerase IIα controls replication origin cluster licensing and firing time in Xenopus egg extracts. , Gaggioli V., Nucleic Acids Res. August 1, 2013; 41 (15): 7313-31.
The Mre11- Rad50- Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks. , Lee J ., Mol Biol Cell. May 1, 2013; 24 (9): 1343-53.
RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks. , Hashimoto Y., Nat Struct Mol Biol. December 4, 2011; 19 (1): 17-24.
Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication. , Kumagai A ., J Cell Biol. June 13, 2011; 193 (6): 995-1007.
MCM2-7 form double hexamers at licensed origins in Xenopus egg extract. , Gambus A., J Biol Chem. April 1, 2011; 286 (13): 11855-64.
Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex. , Kundu LR., Nucleic Acids Res. September 1, 2010; 38 (16): 5409-18.
GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication. , Balestrini A., Nat Cell Biol. May 1, 2010; 12 (5): 484-91.
The DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation. , Chowdhury A., Mol Cell Biol. March 1, 2010; 30 (6): 1495-507.
Treslin collaborates with TopBP1 in triggering the initiation of DNA replication. , Kumagai A ., Cell. February 5, 2010; 140 (3): 349-59.
Tipin/ Tim1/ And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion. , Errico A., EMBO J. December 2, 2009; 28 (23): 3681-92.
Plx1 is required for chromosomal DNA replication under stressful conditions. , Trenz K., EMBO J. March 19, 2008; 27 (6): 876-85.
De novo assembly of genuine replication forks on an immobilized circular plasmid in Xenopus egg extracts. , Zembutsu A., Nucleic Acids Res. July 26, 2006; 34 (13): e91.
The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication. , Matsuno K., Mol Cell Biol. July 1, 2006; 26 (13): 4843-52.
Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress. , Woodward AM., J Cell Biol. June 5, 2006; 173 (5): 673-83.
The DNA polymerase activity of Pol epsilon holoenzyme is required for rapid and efficient chromosomal DNA replication in Xenopus egg extracts. , Shikata K., BMC Biochem. May 1, 2006; 7 21.
Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint. , Petersen P., Mol Cell Biol. March 1, 2006; 26 (5): 1997-2011.
Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication. , Pacek M., Mol Cell. February 17, 2006; 21 (4): 581-7.
Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response. , Lee J ., Mol Biol Cell. November 1, 2005; 16 (11): 5269-82.
Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome. , Sangrithi MN., Cell. June 17, 2005; 121 (6): 887-98.