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The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis. , Guo Y., Dev Biol. May 1, 2019; 449 (1): 1-13.
Frizzled-7 is required for Xenopus heart development. , Abu-Elmagd M., Biol Open. December 15, 2017; 6 (12): 1861-1868.
Id genes are essential for early heart formation. , Cunningham TJ., Genes Dev. July 1, 2017; 31 (13): 1325-1338.
Coordinating heart morphogenesis: A novel role for hyperpolarization-activated cyclic nucleotide-gated (HCN) channels during cardiogenesis in Xenopus laevis. , Pitcairn E., Commun Integr Biol. May 10, 2017; 10 (3): e1309488.
The CapZ interacting protein Rcsd1 is required for cardiogenesis downstream of Wnt11a in Xenopus laevis. , Hempel A., Dev Biol. April 1, 2017; 424 (1): 28-39.
CUG-BP, Elav-like family member 1 (CELF1) is required for normal myofibrillogenesis, morphogenesis, and contractile function in the embryonic heart. , Blech-Hermoni Y., Dev Dyn. August 1, 2016; 245 (8): 854-73.
Early ketamine exposure results in cardiac enlargement and heart dysfunction in Xenopus embryos. , Guo R., BMC Anesthesiol. April 18, 2016; 16 23.
Direct nkx2-5 transcriptional repression of isl1 controls cardiomyocyte subtype identity. , Dorn T., Stem Cells. April 1, 2015; 33 (4): 1113-29.
Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells. , Liu Y ., Stem Cells. June 1, 2014; 32 (6): 1515-26.
Tcf21 regulates the specification and maturation of proepicardial cells. , Tandon P ., Development. June 1, 2013; 140 (11): 2409-21.
Dissociation of cardiogenic and postnatal myocardial activities of GATA4. , Gallagher JM., Mol Cell Biol. June 1, 2012; 32 (12): 2214-23.
Tbx5 overexpression favors a first heart field lineage in murine embryonic stem cells and in Xenopus laevis embryos. , Herrmann F., Dev Dyn. December 1, 2011; 240 (12): 2634-45.
Focal adhesion kinase is essential for cardiac looping and multichamber heart formation. , Doherty JT., Genesis. August 1, 2010; 48 (8): 492-504.
Early activation of FGF and nodal pathways mediates cardiac specification independently of Wnt/beta-catenin signaling. , Samuel LJ., PLoS One. October 28, 2009; 4 (10): e7650.
NFAT directly regulates Nkx2-5 transcription during cardiac cell differentiation. , Chen Y , Chen Y ., Biol Cell. June 1, 2009; 101 (6): 335-49.
Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5. , Espinoza-Lewis RA., Dev Biol. March 15, 2009; 327 (2): 376-85.
Cardiac differentiation in Xenopus requires the cyclin-dependent kinase inhibitor, p27Xic1. , Movassagh M., Cardiovasc Res. August 1, 2008; 79 (3): 436-47.
IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis. , Zhu W., Nature. July 17, 2008; 454 (7202): 345-9.
XHAPLN3 plays a key role in cardiogenesis by maintaining the hyaluronan matrix around heart anlage. , Ito Y ., Dev Biol. July 1, 2008; 319 (1): 34-45.
A crucial role of a high mobility group protein HMGA2 in cardiogenesis. , Monzen K., Nat Cell Biol. May 1, 2008; 10 (5): 567-74.
HIF-1alpha signaling upstream of NKX2.5 is required for cardiac development in Xenopus. , Nagao K., J Biol Chem. April 25, 2008; 283 (17): 11841-9.
Redundancy and evolution of GATA factor requirements in development of the myocardium. , Peterkin T., Dev Biol. November 15, 2007; 311 (2): 623-35.
Xenopus as a model system for vertebrate heart development. , Warkman AS ., Semin Cell Dev Biol. February 1, 2007; 18 (1): 46-53.
Myoskeletin, a factor related to Myocardin, is expressed in somites and required for hypaxial muscle formation in Xenopus. , Zhao H ., Int J Dev Biol. January 1, 2007; 51 (4): 315-20.
Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart. , Wu SM ., Cell. December 15, 2006; 127 (6): 1137-50.
Retinoic acid signaling is essential for formation of the heart tube in Xenopus. , Collop AH., Dev Biol. March 1, 2006; 291 (1): 96-109.
Myocardin is sufficient and necessary for cardiac gene expression in Xenopus. , Small EM ., Development. March 1, 2005; 132 (5): 987-97.
Wnt11 facilitates embryonic stem cell differentiation to Nkx2.5-positive cardiomyocytes. , Terami H., Biochem Biophys Res Commun. December 17, 2004; 325 (3): 968-75.
Myocardin expression is regulated by Nkx2.5, and its function is required for cardiomyogenesis. , Ueyama T., Mol Cell Biol. December 1, 2003; 23 (24): 9222-32.
Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart. , Stennard FA ., Dev Biol. October 15, 2003; 262 (2): 206-24.
Amphibian in vitro heart induction: a simple and reliable model for the study of vertebrate cardiac development. , Ariizumi T., Int J Dev Biol. September 1, 2003; 47 (6): 405-10.
Transgenic analysis of the atrialnatriuretic factor ( ANF) promoter: Nkx2-5 and GATA-4 binding sites are required for atrial specific expression of ANF. , Small EM ., Dev Biol. September 1, 2003; 261 (1): 116-31.
Csm, a cardiac-specific isoform of the RNA helicase Mov10l1, is regulated by Nkx2.5 in embryonic heart. , Ueyama T., J Biol Chem. August 1, 2003; 278 (31): 28750-7.
Chamber-specific differentiation of Nkx2.5-positive cardiac precursor cells from murine embryonic stem cells. , Hidaka K., FASEB J. April 1, 2003; 17 (6): 740-2.
Nkx2.5 homeoprotein regulates expression of gap junction protein connexin 43 and sarcomere organization in postnatal cardiomyocytes. , Kasahara H., J Mol Cell Cardiol. March 1, 2003; 35 (3): 243-56.
Cardiomyogenic differentiation in cardiac myxoma expressing lineage-specific transcription factors. , Kodama H., Am J Pathol. August 1, 2002; 161 (2): 381-9.
Csx/ Nkx2-5 is required for homeostasis and survival of cardiac myocytes in the adult heart. , Toko H., J Biol Chem. July 5, 2002; 277 (27): 24735-43.
The Polycomb-group gene Rae28 sustains Nkx2.5/ Csx expression and is essential for cardiac morphogenesis. , Shirai M., J Clin Invest. July 1, 2002; 110 (2): 177-84.
Differential regulation of the cardiac sodium calcium exchanger promoter in adult and neonatal cardiomyocytes by Nkx2.5 and serum response factor. , Müller JG., J Mol Cell Cardiol. July 1, 2002; 34 (7): 807-21.
A role for the RNA-binding protein, hermes, in the regulation of heart development. , Gerber WV ., Dev Biol. July 1, 2002; 247 (1): 116-26.
Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation. , Habets PE., Genes Dev. May 15, 2002; 16 (10): 1234-46.
Nkx-2.5 gene induction in mice is mediated by a Smad consensus regulatory region. , Liberatore CM., Dev Biol. April 15, 2002; 244 (2): 243-56.
Developmental paradigms in heart disease: insights from tinman. , Prall OW., Ann Med. January 1, 2002; 34 (3): 148-56.
Embryonic expression of an Nkx2-5/Cre gene using ROSA26 reporter mice. , Moses KA., Genesis. December 1, 2001; 31 (4): 176-80.
BMP signaling regulates Nkx2-5 activity during cardiomyogenesis. , Jamali M., FEBS Lett. November 30, 2001; 509 (1): 126-30.
The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation. , Yamagishi H., Dev Biol. November 15, 2001; 239 (2): 190-203.
Nkx2-5 activity is essential for cardiomyogenesis. , Jamali M., J Biol Chem. November 9, 2001; 276 (45): 42252-8.
Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/ Nkx2.5 homeoprotein. , Kasahara H., J Clin Invest. July 1, 2001; 108 (2): 189-201.
Elevated expression of Nkx-2.5 in developing myocardial conduction cells. , Thomas PS., Anat Rec. July 1, 2001; 263 (3): 307-13.
Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation. , Hiroi Y., Nat Genet. July 1, 2001; 28 (3): 276-80.