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Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney. , Zhang B., Development. March 22, 2018; 145 (6):
Mitragynine and its potential blocking effects on specific cardiac potassium channels. , Tay YL., Toxicol Appl Pharmacol. August 15, 2016; 305 22-39.
Measuring Absolute RNA Copy Numbers at High Temporal Resolution Reveals Transcriptome Kinetics in Development. , Owens ND., Cell Rep. January 26, 2016; 14 (3): 632-47.
HPLC-Based Activity Profiling for hERG Channel Inhibitors in the South African Medicinal Plant Galenia africana. , Du K., Planta Med. August 1, 2015; 81 (12-13): 1154-62.
Identification and functional characterization of a novel arginine/ornithine transporter, a member of a cationic amino acid transporter subfamily in the Trypanosoma cruzi genome. , Henriques C., Parasit Vectors. June 25, 2015; 8 346.
Anesthetic drug midazolam inhibits cardiac human ether-à- go-go-related gene channels: mode of action. , Vonderlin N., Drug Des Devel Ther. February 16, 2015; 9 867-77.
Up-regulation of hERG K⁺ channels by B-RAF. , Pakladok T., PLoS One. January 1, 2014; 9 (1): e87457.
AMP-activated protein kinase regulates hERG potassium channel. , Almilaji A., Pflugers Arch. November 1, 2013; 465 (11): 1573-82.
Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel. , Park MH., J Pharmacol Sci. September 20, 2013; 123 (1): 67-77.
Exotic models may offer unique opportunities to decipher specific scientific question: the case of Xenopus olfactory system. , Gascuel J ., Anat Rec (Hoboken). September 1, 2013; 296 (9): 1453-61.
Functional interactions of voltage sensor charges with an S2 hydrophobic plug in hERG channels. , Cheng YM., J Gen Physiol. September 1, 2013; 142 (3): 289-303.
External pH modulates EAG superfamily K+ channels through EAG-specific acidic residues in the voltage sensor. , Kazmierczak M., J Gen Physiol. June 1, 2013; 141 (6): 721-35.
Mapping of interactions between the N- and C-termini and the channel core in HERG K+ channels. , de la Peña P., Biochem J. May 1, 2013; 451 (3): 463-74.
Flavonoid regulation of EAG1 channels. , Carlson AE., J Gen Physiol. March 1, 2013; 141 (3): 347-58.
Block of hERG K+ channel and prolongation of action potential duration by fluphenazine at submicromolar concentration. , Hong HK., Eur J Pharmacol. February 28, 2013; 702 (1-3): 165-73.
The eag domain regulates hERG channel inactivation gating via a direct interaction. , Gustina AS., J Gen Physiol. February 1, 2013; 141 (2): 229-41.
Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels. , Tan PS., J Gen Physiol. September 1, 2012; 140 (3): 293-306.
Identification and functional characterization of the novel human ether-a- go-go-related gene ( hERG) R744P mutant associated with hereditary long QT syndrome 2. , Aidery P., Biochem Biophys Res Commun. February 24, 2012; 418 (4): 830-5.
A unified anatomy ontology of the vertebrate skeletal system. , Dahdul WM., PLoS One. January 1, 2012; 7 (12): e51070.
Effects of the histamine H(1) receptor antagonist hydroxyzine on hERG K(+) channels and cardiac action potential duration. , Lee BH., Acta Pharmacol Sin. September 1, 2011; 32 (9): 1128-37.
Ginsenoside Rg(3) decelerates hERG K(+) channel deactivation through Ser631 residue interaction. , Choi SH., Eur J Pharmacol. August 1, 2011; 663 (1-3): 59-67.
Differential effects of ginsenoside metabolites on HERG k channel currents. , Choi SH., J Ginseng Res. June 1, 2011; 35 (2): 191-9.
Shh signalling restricts the expression of Gcm2 and controls the position of the developing parathyroids. , Grevellec A., Dev Biol. May 15, 2011; 353 (2): 194-205.
hERG potassium channel gating is mediated by N- and C-terminal region interactions. , Gustina AS., J Gen Physiol. March 1, 2011; 137 (3): 315-25.
Transfer of ion binding site from ether-a- go-go to Shaker: Mg2+ binds to resting state to modulate channel opening. , Lin MC., J Gen Physiol. May 1, 2010; 135 (5): 415-31.
Block of the human ether-a- go-go-related gene ( hERG) K+ channel by the antidepressant desipramine. , Hong HK., Biochem Biophys Res Commun. April 9, 2010; 394 (3): 536-41.
Inhibition of the human ether-a- go-go-related gene ( HERG) K+ channels by Lindera erythrocarpa. , Hong HK., J Korean Med Sci. December 1, 2009; 24 (6): 1089-98.
Block of HERG k channel by classic histamine h(1) receptor antagonist chlorpheniramine. , Hong HK., Korean J Physiol Pharmacol. June 1, 2009; 13 (3): 215-20.
Blockade of the human ether-a- go-go-related gene potassium channel by ketanserin. , Tu DN., Sheng Li Xue Bao. August 25, 2008; 60 (4): 525-34.
Protriptyline block of the human ether-à- go-go-related gene ( HERG) K+ channel. , Jo SH., Life Sci. January 30, 2008; 82 (5-6): 331-40.
Maprotiline block of the human ether-a- go-go-related gene ( HERG) K+ channel. , Jo SH., Arch Pharm Res. April 1, 2007; 30 (4): 453-60.
Pairing morphology with gene expression in thyroid hormone-induced intestinal remodeling and identification of a core set of TH-induced genes across tadpole tissues. , Buchholz DR ., Dev Biol. March 15, 2007; 303 (2): 576-90.
Structural requirements of human ether-a- go-go-related gene channels for block by bupivacaine. , Siebrands CC., Anesthesiology. March 1, 2007; 106 (3): 523-31.
In vitro modulation of HERG channels by organochlorine solvent trichlormethane as potential explanation for proarrhythmic effects of chloroform. , Scholz EP., Toxicol Lett. August 20, 2006; 165 (2): 156-66.
Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine. , Lee SY., Br J Pharmacol. June 1, 2006; 148 (4): 499-509.
Chemical modification of the human ether-a- go-go-related gene ( HERG) K+ current by the amino-group reagent trinitrobenzene sulfonic acid. , Jo SH., Arch Pharm Res. April 1, 2006; 29 (4): 310-7.
The effects of sevoflurane and propofol on QT interval and heterologously expressed human ether-a- go-go related gene currents in Xenopus oocytes. , Yamada M., Anesth Analg. January 1, 2006; 102 (1): 98-103.
Activation of human ether-a- go-go-related gene potassium channels by the diphenylurea 1,3- bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643). , Hansen RS., Mol Pharmacol. January 1, 2006; 69 (1): 266-77.
Expression and functional characterization of the human ether-à- go-go-related gene ( HERG) K+ channel cardiac splice variant in Xenopus laevis oocytes. , Aydar E., J Membr Biol. January 1, 2006; 211 (2): 115-26.
Inhibitory effect of rhynchophylline on human ether-a- go-go related gene channel. , Gui L., Sheng Li Xue Bao. October 25, 2005; 57 (5): 648-52.
Inhibition of human ether-a- go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine. , Choi SY., J Pharmacol Exp Ther. May 1, 2005; 313 (2): 888-95.
An atlas of differential gene expression during early Xenopus embryogenesis. , Pollet N ., Mech Dev. March 1, 2005; 122 (3): 365-439.
A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a- go-go-related gene ( HERG) channels. , Lin C., Am J Ther. January 1, 2005; 12 (4): 328-36.
Salt bridges and gating in the COOH-terminal region of HCN2 and CNGA1 channels. , Craven KB., J Gen Physiol. December 1, 2004; 124 (6): 663-77.
Open channel block by KCB-328 [1-(2-amino-4-methanesulfonamidophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane hydrochloride] of the heterologously expressed human ether-a- go-go-related gene K+ channels. , Park JB ., J Pharmacol Exp Ther. July 1, 2002; 302 (1): 314-9.
Antiarrhythmic drug carvedilol inhibits HERG potassium channels. , Karle CA., Cardiovasc Res. February 1, 2001; 49 (2): 361-70.
Mg(2+) modulates voltage-dependent activation in ether-à- go-go potassium channels by binding between transmembrane segments S2 and S3. , Silverman WR., J Gen Physiol. November 1, 2000; 116 (5): 663-78.
Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function. , Brickman JM ., Development. June 1, 2000; 127 (11): 2303-15.
Blockade of the HERG human cardiac K(+) channel by the antidepressant drug amitriptyline. , Jo SH., Br J Pharmacol. April 1, 2000; 129 (7): 1474-80.
Extracellular Mg(2+) modulates slow gating transitions and the opening of Drosophila ether-à- Go-Go potassium channels. , Tang CY ., J Gen Physiol. March 1, 2000; 115 (3): 319-38.