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Summary Anatomy Item Literature (1190) Expression Attributions Wiki
XB-ANAT-721

Papers associated with distal (and wnk1)

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Role of KLHL3 and dietary K+ in regulating KS-WNK1 expression., Ostrosky-Frid M., Am J Physiol Renal Physiol. May 1, 2021; 320 (5): F734-F747.                    

Mutation affecting the conserved acidic WNK1 motif causes inherited hyperkalemic hyperchloremic acidosis., Louis-Dit-Picard H., J Clin Invest. December 1, 2020; 130 (12): 6379-6394.

Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC., Argaiz ER., Am J Physiol Renal Physiol. September 1, 2018; 315 (3): F734-F745.

A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo., Oi K., Biol Open. February 15, 2012; 1 (2): 120-7.              

Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models., Liu Z., Hum Mol Genet. March 1, 2011; 20 (5): 855-66.

The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex., Yang CL., J Clin Invest. November 1, 2007; 117 (11): 3403-11.

WNK4-mediated regulation of renal ion transport proteins., Peng JB., Am J Physiol Renal Physiol. October 1, 2007; 293 (4): F961-73.

Dietary electrolyte-driven responses in the renal WNK kinase pathway in vivo., O'Reilly M., J Am Soc Nephrol. September 1, 2006; 17 (9): 2402-13.

Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform., Subramanya AR., Am J Physiol Renal Physiol. March 1, 2006; 290 (3): F619-24.

WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis., Rinehart J., Proc Natl Acad Sci U S A. November 15, 2005; 102 (46): 16777-82.

[WNK1 and WNK4, new players in salt and water homeostasis], Hadchouel J., Med Sci (Paris). January 1, 2005; 21 (1): 55-60.

WNK kinases regulate thiazide-sensitive Na-Cl cotransport., Yang CL., J Clin Invest. April 1, 2003; 111 (7): 1039-45.

Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4., Wilson FH., Proc Natl Acad Sci U S A. January 21, 2003; 100 (2): 680-4.

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