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Bioelectric signaling: Reprogrammable circuits underlying embryogenesis, regeneration, and cancer. , Levin M ., Cell. April 15, 2021;
Toward a Structural View of hERG Activation by the Small-Molecule Activator ICA-105574. , Zangerl-Plessl EM., J Chem Inf Model. January 27, 2020; 60 (1): 360-371.
Fluorescent analogues of BeKm-1 with high and specific activity against the hERG channel. , Vasseur L., Toxicon X. February 23, 2019; 2 100010.
Molecular Basis of Altered hERG1 Channel Gating Induced by Ginsenoside Rg3. , Gardner A., Mol Pharmacol. October 1, 2017; 92 (4): 437-450.
Molecular Cloning and Functional Expression of the Equine K+ Channel KV11.1 (Ether à Go-Go-Related/KCNH2 Gene) and the Regulatory Subunit KCNE2 from Equine Myocardium. , Pedersen PJ., PLoS One. September 4, 2015; 10 (9): e0138320.
Marine algal toxin azaspiracid is an open-state blocker of hERG potassium channels. , Twiner MJ., Chem Res Toxicol. September 17, 2012; 25 (9): 1975-84.
Recombinant expression of the toxic peptide ErgTx1 and role of Met35 on its stability and function. , Jimenez-Vargas JM., Peptides. March 1, 2011; 32 (3): 560-7.
Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current. , Larsen AP., Pflugers Arch. September 1, 2008; 456 (6): 1137-48.
Probing the binding sites and mechanisms of action of two human ether-a- go-go-related gene channel activators, 1,3- bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243). , Xu X., Mol Pharmacol. June 1, 2008; 73 (6): 1709-21.
Probing the outer mouth structure of the HERG channel with peptide toxin footprinting and molecular modeling. , Tseng GN., Biophys J. May 15, 2007; 92 (10): 3524-40.
Upregulation of KCNE1 induces QT interval prolongation in patients with chronic heart failure. , Watanabe E., Circ J. April 1, 2007; 71 (4): 471-8.
[Electrophysiological characterization of long QT syndrome associated mutations V630A and N633S]. , She HR., Zhonghua Xin Xue Guan Bing Za Zhi. June 1, 2006; 34 (6): 523-7.
Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels. , Clarke CE., J Physiol. June 1, 2006; 573 (Pt 2): 291-304.
Structure-function studies of the outer mouth and voltage sensor domain of hERG. , Tseng GN., Novartis Found Symp. January 1, 2005; 266 19-35; discussion 35-45.
Gating charges in the activation and inactivation processes of the HERG channel. , Zhang M., J Gen Physiol. December 1, 2004; 124 (6): 703-18.
Structural and functional role of the extracellular s5-p linker in the HERG potassium channel. , Liu J ., J Gen Physiol. November 1, 2002; 120 (5): 723-37.
[Cardiotoxicity of lindane, a gamma isomer of hexachlorocyclohexane]. , Sauviat MP., J Soc Biol. January 1, 2002; 196 (4): 339-48.
Characterization of a novel Kv1.5 channel blocker in Xenopus oocytes, CHO cells, human and rat cardiomyocytes. , Bachmann A., Naunyn Schmiedebergs Arch Pharmacol. November 1, 2001; 364 (5): 472-8.
Use-dependent 'agonist' effect of azimilide on the HERG channel. , Jiang M., J Pharmacol Exp Ther. December 1, 1999; 291 (3): 1324-36.
Effects of outer mouth mutations on hERG channel function: a comparison with similar mutations in the Shaker channel. , Fan JS., Biophys J. June 1, 1999; 76 (6): 3128-40.
Regulation of deactivation by an amino terminal domain in human ether-à- go-go-related gene potassium channels. , Wang J ., J Gen Physiol. November 1, 1998; 112 (5): 637-47.
Novel mechanism of HERG current suppression in LQT2: shift in voltage dependence of HERG inactivation. , Nakajima T., Circ Res. August 24, 1998; 83 (4): 415-22.
Differential effects of bupivacaine on cardiac K channels: role of channel inactivation and subunit composition in drug-channel interaction. , Lipka LJ., J Cardiovasc Electrophysiol. July 1, 1998; 9 (7): 727-42.
Modulation of HERG affinity for E-4031 by [K+]o and C-type inactivation. , Wang S., FEBS Lett. November 3, 1997; 417 (1): 43-7.
Tissue and species distribution of mRNA for the IKr-like K+ channel, erg. , Wymore RS., Circ Res. February 1, 1997; 80 (2): 261-8.
HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine. , Roy M., Circulation. August 15, 1996; 94 (4): 817-23.
Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel. , Schönherr R., J Physiol. June 15, 1996; 493 ( Pt 3) 635-42.