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Summary Anatomy Item Literature (3130) Expression Attributions Wiki
XB-ANAT-821

Papers associated with kidney (and pkd2)

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The diverse effects of pathogenic point mutations on ion channel activity of a gain-of-function polycystin-2., Wang Y., J Biol Chem. May 1, 2023; 299 (5): 104674.


Regulation of PKD2 channel function by TACAN., Liu X., J Physiol. January 1, 2023; 601 (1): 83-98.


Deep learning is widely applicable to phenotyping embryonic development and disease., Naert T., Development. November 1, 2021; 148 (21):                                                                 


A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts., Grosch M., J Cell Sci. August 15, 2021; 134 (16):                 


Aquatic models of human ciliary diseases., Corkins ME., Genesis. February 1, 2021; 59 (1-2): e23410.          


The ion channel function of polycystin-1 in the polycystin-1/polycystin-2 complex., Wang Z., EMBO Rep. November 5, 2019; 20 (11): e48336.                            


A PKD1L3 splice variant in taste buds is not cleaved at the G protein-coupled receptor proteolytic site., Kashyap P., Biochem Biophys Res Commun. May 14, 2019; 512 (4): 812-818.            


Modeling congenital kidney diseases in Xenopus laevis., Blackburn ATM., Dis Model Mech. April 9, 2019; 12 (4):       


Characterization of potential TRPP2 regulating proteins in early Xenopus embryos., Futel M., J Cell Biochem. December 1, 2018; 119 (12): 10338-10350.  


Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels., Zheng W., Nat Commun. June 13, 2018; 9 (1): 2302.            


An Early Function of Polycystin-2 for Left-Right Organizer Induction in Xenopus., Vick P., iScience. April 27, 2018; 2 76-85.                                        


Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney., Zhang B., Development. March 22, 2018; 145 (6):                         


The Sorting Nexin 3 Retromer Pathway Regulates the Cell Surface Localization and Activity of a Wnt-Activated Polycystin Channel Complex., Feng S., J Am Soc Nephrol. October 1, 2017; 28 (10): 2973-2984.


The polycystin complex mediates Wnt/Ca(2+) signalling., Kim S., Nat Cell Biol. July 1, 2016; 18 (7): 752-764.              


Using Xenopus to study genetic kidney diseases., Lienkamp SS., Semin Cell Dev Biol. March 1, 2016; 51 117-24.    


Hereditary Renal Hypouricemia Type 1 and Autosomal Dominant Polycystic Kidney Disease., Stiburkova B., Am J Med Sci. October 1, 2015; 350 (4): 268-71.


TRPP2-dependent Ca2+ signaling in dorso-lateral mesoderm is required for kidney field establishment in Xenopus., Futel M., J Cell Sci. March 1, 2015; 128 (5): 888-99.                      


Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation., Streets AJ., Hum Mol Genet. May 15, 2013; 22 (10): 1924-39.


Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex., Yu Y., Nat Commun. January 1, 2012; 3 1252.            


Polycystin-2 activity is controlled by transcriptional coactivator with PDZ binding motif and PALS1-associated tight junction protein., Duning K., J Biol Chem. October 29, 2010; 285 (44): 33584-8.


Identification of a polycystin-1 cleavage product, P100, that regulates store operated Ca entry through interactions with STIM1., Woodward OM., PLoS One. August 23, 2010; 5 (8): e12305.              


The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity., Tran U., Development. April 1, 2010; 137 (7): 1107-16.              


Polycystin-1 interacts with inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling with implications for polycystic kidney disease., Li Y., J Biol Chem. December 25, 2009; 284 (52): 36431-36441.


Structural and molecular basis of the assembly of the TRPP2/PKD1 complex., Yu Y., Proc Natl Acad Sci U S A. July 14, 2009; 106 (28): 11558-63.


TRPP2 channels regulate apoptosis through the Ca2+ concentration in the endoplasmic reticulum., Wegierski T., EMBO J. March 4, 2009; 28 (5): 490-9.


Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants., Sullivan-Brown J., Dev Biol. February 15, 2008; 314 (2): 261-75.


Polycystic kidney disease and receptor for egg jelly is a plasma membrane protein of mouse sperm head., Butscheid Y., Mol Reprod Dev. March 1, 2006; 73 (3): 350-60.


Inhibition of polycystin-L channel by the Chinese herb Sparganum stoloniferum Buch.-Ham., Li F., Can J Physiol Pharmacol. January 1, 2006; 84 (8-9): 923-7.


Polycystin 2 interacts with type I inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling., Li Y., J Biol Chem. December 16, 2005; 280 (50): 41298-306.


Cloning and expression of the amphibian homologue of the human PKD1 gene., Burtey S., Gene. August 29, 2005; 357 (1): 29-36.          


Expression of the polycystin-1 C-terminal cytoplasmic tail increases Cl channel activity in Xenopus oocytes., Chernova MN., Kidney Int. August 1, 2005; 68 (2): 632-41.


A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney., Sun Z., Development. August 1, 2004; 131 (16): 4085-93.


Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization., Cano DA., Development. July 1, 2004; 131 (14): 3457-67.


Evolutionary conservation of Drosophila polycystin-2 as a calcium-activated cation channel., Venglarik CJ., J Am Soc Nephrol. May 1, 2004; 15 (5): 1168-77.


Native polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epithelia., Luo Y., Mol Cell Biol. April 1, 2003; 23 (7): 2600-7.


Polycystin-2 associates with tropomyosin-1, an actin microfilament component., Li Q., J Mol Biol. January 31, 2003; 325 (5): 949-62.


Polycystin-2 interacts with troponin I, an angiogenesis inhibitor., Li Q., Biochemistry. January 21, 2003; 42 (2): 450-7.


Cation channel regulation by COOH-terminal cytoplasmic tail of polycystin-1: mutational and functional analysis., Vandorpe DH., Physiol Genomics. February 28, 2002; 8 (2): 87-98.


Transport function of the naturally occurring pathogenic polycystin-2 mutant, R742X., Chen XZ., Biochem Biophys Res Commun. April 20, 2001; 282 (5): 1251-6.


Polycystin-2 is a novel cation channel implicated in defective intracellular Ca(2+) homeostasis in polycystic kidney disease., Vassilev PM., Biochem Biophys Res Commun. March 23, 2001; 282 (1): 341-50.


Polycystin-L is a calcium-regulated cation channel permeable to calcium ions., Chen XZ., Nature. September 23, 1999; 401 (6751): 383-6.

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