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Nedd4-2 regulates surface expression and may affect N-glycosylation of hyperpolarization-activated cyclic nucleotide-gated (HCN)-1 channels. , Wilkars W., FASEB J. May 1, 2014; 28 (5): 2177-90.
WNK4 inhibition of ENaC is independent of Nedd4-2-mediated ENaC ubiquitination. , Yu L., Am J Physiol Renal Physiol. July 1, 2013; 305 (1): F31-41.
AMP-activated protein kinase downregulates Kv7.1 cell surface expression. , Andersen MN., Traffic. January 1, 2012; 13 (1): 143-56.
Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone- SGK1- Nedd4-2 pathway. , Arroyo JP., J Am Soc Nephrol. September 1, 2011; 22 (9): 1707-19.
AMP-activated protein kinase inhibits KCNQ1 channels through regulation of the ubiquitin ligase Nedd4-2 in renal epithelial cells. , Alzamora R., Am J Physiol Renal Physiol. December 1, 2010; 299 (6): F1308-19.
COMMD1 downregulates the epithelial sodium channel through Nedd4-2. , Ke Y., Am J Physiol Renal Physiol. June 1, 2010; 298 (6): F1445-56.
A human polymorphism affects NEDD4L subcellular targeting by leading to two isoforms that contain or lack a C2 domain. , Garrone NF., BMC Cell Biol. April 13, 2009; 10 26.
Functional regulation of the epithelial Na+ channel by IkappaB kinase-beta occurs via phosphorylation of the ubiquitin ligase Nedd4-2. , Edinger RS., J Biol Chem. January 2, 2009; 284 (1): 150-157.
Expression, transcription, and possible antagonistic interaction of the human Nedd4L gene variant: implications for essential hypertension. , Araki N., Hypertension. March 1, 2008; 51 (3): 773-7.
Early aldosterone-induced gene product regulates the epithelial sodium channel by deubiquitylation. , Fakitsas P., J Am Soc Nephrol. April 1, 2007; 18 (4): 1084-92.
Aldosterone-induced serum and glucocorticoid-induced kinase 1 expression is accompanied by Nedd4-2 phosphorylation and increased Na+ transport in cortical collecting duct cells. , Flores SY., J Am Soc Nephrol. August 1, 2005; 16 (8): 2279-87.
Role of Nedd4-2 and polyubiquitination in epithelial sodium channel degradation in untransfected renal A6 cells expressing endogenous ENaC subunits. , Malik B., Am J Physiol Renal Physiol. July 1, 2005; 289 (1): F107-16.
Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells. , Hryciw DH., J Biol Chem. December 31, 2004; 279 (53): 54996-5007.
Regulation of CLC-Ka/ barttin by the ubiquitin ligase Nedd4-2 and the serum- and glucocorticoid-dependent kinases. , Embark HM., Kidney Int. November 1, 2004; 66 (5): 1918-25.