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Summary Anatomy Item Literature (7335) Expression Attributions Wiki

Anatomy Term: brain
XAO ID: 0000010
Definition: "Organ that is a component of the central nervous system and is responsible for the coordination and control of bodily activities and the interpretation of information from the senses. It appears when the neural tube segregates in forebrain, midbrain, and hindbrain at NF stage 22. The general pattern of the brain has been mainly established at NF stage 28. Yolky material is consumed and the fibre tracts and later the commissures develop. In general all of its parts are well developed at NF stage 53 and later development consists mainly of growth and some further cytological differentiation. In the period of metamorphosis only topographical changes take place."
Stage Range: NF stage 22 to death
Marker Genes: sox3 gjc1 s1pr1 nrcam
Antibody: Ache AB1 Arl13b Ab3 B3gat1 Ab5 CaMK2a Ab4 Chat Ab1 Cntn1 Ab1 Cntn1 Ab2 Cntn1 Ab3 Dcx Ab1 Dlx2 Ab1 Dyrk1a Ab1 Fabp7 Ab1 GABA Ab2 Gja1 Ab1 Glul Ab1 L1cam Ab1 Lsamp Ab1 NOC-2 Ab2 Ncam1 Ab4 Nf2 Ab1 Nkx2-1 Ab2 Nr3c1 Ab1 Otp Ab1 Pax7 Ab1 Pomc Ab1 Ptpra Ab1 Rab11a Ab1 Rbfox3 Ab1 Slc5a10 Ab1 Stx1a Ab1 Syp Ab1 Th Ab1 Th Ab2 Thra-Thrb Ab1 Tnc Ab2 Tuba4b Ab11
Develops From:
Anatomy Item Stage Range
neural tube NF stage 17 to NF stage 28
Develops Into:
Parent(s): neural tube


Parent(s): cavitated compound organ (is_a) central nervous system (part_of) head (part_of)


References: NCBO BioPortal , Ontology Lookup Service