Anatomy Term: neural crest
XAO ID: 0000048
Synonyms: neural crest material, NC
Definition: "A group of ectoderm cells that delaminate from the area between the neuroectoderm/non-neural ectoderm domains. They undergo epithelial-to-mesenchymal tranformation (EMT) and migrate to give several different lineages of adult cells. Originating from different positions along the anterior-posterior axis, they develop into various tissues. These regions of neural crest can be divided into five main functional domains, which include the cranial, trunk, vagal and sacral neural crest, and cardiac neural crest. Neural crest cells are considered multipotent, and as they have the limited capacity for self renewal, they are regarded as stem cell-like."
Stage Range: NF stage 13 to NF stage 44
Component Anatomy Items:
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References: NCBO BioPortal, Ontology Lookup Service