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Summary Anatomy Item Literature (1183) Expression Attributions Wiki
XB-ANAT-48

Anatomy Term: neural crest

XAO ID: 0000048

Synonyms: neural crest material, NC

Definition: "A group of ectoderm cells that delaminate from the area between the neuroectoderm/non-neural ectoderm domains. They undergo epithelial-to-mesenchymal tranformation (EMT) and migrate to give several different lineages of adult cells. Originating from different positions along the anterior-posterior axis, they develop into various tissues. These regions of neural crest can be divided into five main functional domains, which include the cranial, trunk, vagal and sacral neural crest, and cardiac neural crest. Neural crest cells are considered multipotent, and as they have the limited capacity for self renewal, they are regarded as stem cell-like."


Stage Range: NF stage 13 to NF stage 44

Marker Genes:


Develops From:
Anatomy Item Stage Range
ectoderm NF stage 10 to NF stage 66
neural plate border NF stage 11.5 to NF stage 22
Develops Into:
Anatomy Item Stage Range
migratory neural crest cell NF stage 13 to NF stage 31
glial cell NF stage 22 to death
melanoblast NF stage 26 to NF stage 32
enteric neuron NF stage 20 to death

Component Anatomy Items:

is a part of derives from

References: NCBO BioPortal, Ontology Lookup Service

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