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| G protein | tyrosine kinase | wnt | Notch | TGF/SMAD | hedgehog | |
cell biology: signal transduction via RTKs
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click on a molecule to obtain more information and references |
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mitogens trophins |
inflammatory cytokines |
stress | |||||
| receptor tyrosine kinase |
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| GRB2 | GCK1 | Rac/ cdc 42 | PAK | ||||
| GNRF | MLK1-4 | ||||||
| ras | MEKK-X | ||||||
| MKK3/6 | |||||||
| raf (MAPKKK) | MEKK1-5 | p38 abg | |||||
| MEK (MAPKK) | SEK 1/2 | ||||||
| SAPK abg | MAPKAPK2 | ||||||
| MAPK |
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| Elk1 | c-Jun | ATF-2 | hsp27 | ||||
| p85 rsk | |||||||
| downstream genes |
pathway data from Jim Woodget's site at the University of Toronto
Last update February 16, 2006
page administrator, Malcolm Whitman
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| community | gene expression | genomics | genetics | atlas/movies/fate | cell biology |
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