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Figure 5. Mg2+-evoked currents in Xenopus oocytes expressing hMagT1. Current-voltage relationships obtained from linear voltage steps from -150 mV to +25 mV in the presence of Mg2+-free solutions or those containing the indicated concentrations of MgCl2. Oocytes were clamped at a holding potential of -15 mV and stepped from -150 mV to +25 mV in 25 mV increments for 2 s at each of the concentrations indicated. Shown are average I-V curves obtained from control H2O-injected (n = 13) or MagT1-expressing (n =/>7) oocytes. Note, the positive shift in reversal potential, indicated by arrows, with increments in magnesium concentration. Values are mean ± SEM of observations measured at the end of each voltage sweep for the respective Mg2+ concentration. Image published in: Goytain A and Quamme GA (2005) Copyright © 2005 Goytain and Quamme; licensee BioMed Central Ltd. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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