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Figure 10. Inhibition of MagT1-mediated currents. A,inhibition of Mg2+-evoked currents with 0.2 mM test cation in the presence of external 2.0 mM Mg2+. For clarity, only Cu2+, Mn3+, and Zn2+ relative to Mg2+ are represented. Values are mean ± SEM of currents measured at the end of each voltage sweep for the respective cation. B, summary of inhibition by multivalent cations of Mg2+ currents based on the change in Erev represented in Fig. 10A. The inhibitor was added with MgCl2 and voltage-clamp was performed about 5 min later. Image published in: Goytain A and Quamme GA (2005) Copyright © 2005 Goytain and Quamme; licensee BioMed Central Ltd. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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