XB-IMG-116536
Xenbase Image ID: 116536
Figure 3. Deletion analysis maps a BRE to a 68 bp region upstream of the gata2 promoter. A progressive series of 5′ deletions was used to measure the relative activity of the promoter when injected with RNA encoding BMP4, compared to the same reporter when injected with non-coding control RNA, as described in Materials and Methods. For each construct, the site of truncation is indicated, the +1 indicates the transcriptional start site, and the box represents the firefly luciferase reporter. The fold difference (induced/uninduced) is plotted and shows a significant drop when sequences are deleted between −819 and −751. This 68 bp sequence is designated BRE1. Image published in: Oren T et al. (2005) Image downloaded from an Open Access article in PubMed Central. © The Author 2005. Published by Oxford University Press. All rights reserved Larger Image Printer Friendly View |