Xenbase Image ID: 116537

Figure 4. BRE1 mediates activation by BMP4 or Smads. The inducible reporter (−819) or the reporter lacking BRE1 (−751), as diagrammed in Figure 3, was co-injected into Xenopus embryos with RNA encoding Smad1, BMP4, Smad5 or Smad8, as indicated. Smad1 activates the reporter equivalent to BMP4, and in both cases this is dependent on the presence of the BRE1 sequences. Smad5 is only slightly less active, while Smad8 fails to induce reporter activity. Image published in: Oren T et al. (2005) Image downloaded from an Open Access article in PubMed Central. © The Author 2005. Published by Oxford University Press. All rights reserved Larger Image Printer Friendly View

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