Xenbase Image ID: 116758

Figure 4. Nonsynonymous Substitutions in Each X. laevis Paralog (α and β) and the Diploid Lineage in Representative GenesSubstitutions in the diploid lineage (d) occurred on the thick branches in the rooted topologies to the left of each locus. (A) liver-type arginase, (B) fibroblast growth factor receptor (FGFR), (C) embryonic fibroblast growth factor (EFGF), and (D) FTZ-F1–related orphan receptor. In (A) a gap indicates a single amino acid deletion, an arrow above the paralog indicates a single amino acid insertion, and this paralog is shortened due to an early stop codon. In (B) three red boxes and a blue box indicate three immunoglobulin domains and a tyrosine kinase domain. In (C) arrows below the paralog indicate predicted cleavage sites in each paralog [79]. In (D) yellow, green, and two lighter blue boxes indicate the DNA-binding C-domain, FTZ-F1 box, and DNA binding domain regions II and III [80]. Image published in: Chain FJ and Evans BJ (2006) Copyright: © 2006 Chain and Evans. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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