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Figure 8. X-TSK changes local response to Xnr2.(A) Whole mount in situ hybridization of Xbra, Gsc (dorsal orientation) Sox17α and GATA4 in embryos injected with 500 pg β-Gal with 50 pg Xnr2, and 50 pg Xnr2 with 1ng X-TSK and 500 pg X-TSK, lateral orientation. Xbra expression is not detected in Xnr2-X-TSK expressing cells, as identified by β-Gal staining. Xnr2 mediated expansion of Gsc expression is enhanced by X-TSK. Expression of endoderm markers Sox17α and GATA4 expanded by Xnr2 is enhanced by X-TSK, suggesting that X-TSK changes local cellular response to Xnr2. Image published in: Morris SA et al. (2007) Morris et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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