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Figure 5. Uncoupled NO3− and SCN− fluxes by slc26a3. Xenopus oocytes expressing slc26a3 were bathed in HEPES-buffered (A) or HCO3−-buffered media (B and C). As indicated by the solid bars, they were exposed to Cl−-free media, and, after the stabilization of pHi, the rates of Cl−/HCO3− and NO3−/HCO3− exchange (B) or Cl−/HCO3− and SCN−/HCO3− exchange (C) were compared, as marked by the gray areas. In each panel, the changes in membrane potential are shown in the top trace, and the changes in pHi are shown in the bottom trace. Note the slow NO3−/HCO3− exchange and the very slow SCN−/HCO3− exchange. The number of experiments and means are given in the text.

Image published in: Shcheynikov N et al. (2006)

Copyright © 2006, The Rockefeller University Press. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license

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