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Figure 3. Activation of dSlo1 saturates around 89 μM [Ca2+]i. (A and B) Current traces of dSlo1 for indicated [Ca2+]i elicited by voltages from −150 to 200 mV. (C) Steady-state G-V curves of dSlo1. Solid curves are fits of the Boltzmann equation. V1/2 obtained from the fits of the G-V relations at each [Ca2+]i is indicated. Dotted lines indicate MWC model simulations of the G-V relation at [Ca2+]i 89, 100, 200, and 300 μM using the same parameters as indicated in Fig. 10 C. Image published in: Krishnamoorthy G et al. (2005) Copyright © 2005, The Rockefeller University Press. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View |