Xenbase Image ID: 124286

Figure 2. Characterization of cyst origin in Wnt9bneo/neo kidneysSections of P1 (a, b, e, f, i, j) and P15 (c, d, g, h, k, l) kidneys stained with the collecting duct specific marker Dolichos biflorus agglutinin (DBA) in a–d, the loop of Henle marker Tamm Horsfall protein (THP) in e–h, and the proximal tubule marker Lotus tetragolonobus lectin (LTL) in i–l. In all panels arrows denote normal tubules and asterisks denote cystic tubules. At birth, cysts are found primarily in the proximal tubules (compare i to j). Cysts are also found in the collecting ducts although the majority of DBA positive epithelia appear normal (see arrows in b). Cysts were not observed in the loop of Henle at birth (compare e to f). By P15 cysts are present in all segments of the nephron (compare c to b, g to h, and k to l). Nuclei were counterstained with DAPI (blue). Image published in: Karner CM et al. (2009) Image downloaded from an Open Access article in PubMed Central. Image reproduced on Xenbase with permission of the publisher and the copyright holder. Larger Image Printer Friendly View

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