Xenbase Image ID: 124287

Figure 3. Cell division becomes oriented after birth in a Wnt9b–dependent process(a) Graphical representation of the angle between the mitotic spindles and the longitudinal axis of DBA-positive tubules at E15.5 indicates that cell division in both wild type (black bars) and Wnt9bneo/neo tubules (white bars) is randomly oriented at E15.5 when compared to the expected random distribution by the Kolmogorov-Smirnov (KS) test. P > 0.55 for both wild type (N=109) and mutant (n=96). (b) At P5, the orientation of dividing cells in KspCre;Wnt9b−/flox DBA positive cells (white bars, n=50) is significantly different (p < 0.01, Mann-Whitney U test) from wild type (black bars, n=45) indicating that Wnt9b is necessary for orientation of cell division that occurs post-natally. Image published in: Karner CM et al. (2009) Image downloaded from an Open Access article in PubMed Central. Image reproduced on Xenbase with permission of the publisher and the copyright holder. Larger Image Printer Friendly View

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