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Figure 13. Simulated curves of a Boltzmann function (gray curve) and of the three-state ion displacement model (black curve), both for the case of a positively charged intracellular blocker. The Boltzmann curve was generated from Eq. 1 with [B] = 5 mM, appKd = 6.5 mM, and Z = 1. The black curve was generated from Eq. 7 with [B] = 5 mM, [Na+] = 130 mM, KB = 1 mM, KB-Na = 0.05, and Z = 1. Image published in: Martínez-François JR and Lu Z (2010) © 2010 Martínez-François and Lu. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View

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