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Figure 14. Models for multistate channel block. Binding of a blocker denoted as “B” to a channel (Ch) produces two blocked states (ChB1 and ChB2) in sequential (A) or parallel (B) steps. Kx are equilibrium constants with effective valences Zx; kx are rate constants and zx their effective valences. Image published in: Martínez-François JR and Lu Z (2010) © 2010 Martínez-François and Lu. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View |