Xenbase Image ID: 125692

Figure 4. Histograms for lengths of nucleosomal DNA (nsDNA) wrapped around histone cores.Nucleosomes were reconstituted using native H4 histone (a), K12C-H4 mutant (b) or K12Cbio-H4 histone (c). It can be seen that in nucleosomes made with K12Cbio-H4 wDNA is shifted towards higher value compared to samples reconstituted using non-biotinylated native H4 or K12C-H4 mutant. The mean values of nsDNA indicated with arrows were 49.8 nm ±1.5 nm, 48.8 nm ±1.4 nm and 56.6 nm ±1.1 nm for NCP containing native histone H4, K12C-H4 mutant, and K12Cbio-H4, respectively. Image published in: Filenko NA et al. (2011) Filenko et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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