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Figure 5. Effect of a β2AR partial agonist on β2-K-62-25.Concentration-effect curves for salbutamol measured in oocytes co-expressing the indicated proteins. Values are average of 3-7 measurements. The smooth line is a Hill equation fit to the β2-K-62-25+TMD0 data with EC50 = 452 nM and h = 0.6. Data obtained with the unfused Kir6.2 as a control could not be fitted. Image published in: Caro LN et al. (2011) Caro et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View |