Xenbase Image ID: 125891

Fig. 1. Structures of the compounds used in this study (Panel A), and an alignment of human Cys-loop receptor M2 regions (Panel B). The alignment includes the human 5-HT3 receptor A and B subunits in addition to subunits from other Cys-loop receptors that are inhibited by BB, GB and PTX. M2 residues are usually referred to using prime (′) notation, which is shown below the alignment. Accession numbers for the alignment are: 5-HT3A (P46098), 5-HT3B (O95264), glycine α1 (P23415), glycine β2 (P48167), GABAA α1 (P14867), GABAA β1 (P18505), GABAA γ2 (Q8N1C3). Image published in: Thompson AJ et al. (2011) © 2011 Elsevier Ltd. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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