Xenbase Image ID: 126136

Figure 3. DNA methylation does not correlate with reversibility of the Xi before nuclear transfer. Bisulphite analysis of G6pdx, X-GFP and Hprt1 promoter and coding regions in female MEFs, EpiSCs and TS cells. All regulatory regions tested are fully methylated on the Xi of all cell types (black circles), and unmethylated on the Xa allele (open circles). The proportion of methylated CG residues is indicated. No circles represent mutated or missing CpGs. Image published in: Pasque V et al. (2011) Copyright © 2011, European Molecular Biology Organization. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View

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