Xenbase Image ID: 126573

Figure 4. SCCaFTs generated by Aβ1−42 display multiple Ca2+ flux levels. (A) The trace at the left shows a representative record of SCCaFTs induced by Aβ1−42 oligomers, and the trace at the right shows the segment marked by the gray box on an expanded timescale. The bars indicate Ca2+ fluorescence levels (ΔF/F0) corresponding to different amplitude dwell states during SCCaFTs. (B) Distribution of dwell-state amplitude levels during Aβ1−42 SCCaFTs measured by visual inspection of traces from 76 pores selected from a single image record. (C) Distribution of the maximum SCCaFT amplitude observed at a given site generated by CellSpecks from an image sequence that encompassed 2,820 total sites. Data are representative of results from three or more image records obtained in each of four oocytes. Image published in: Demuro A et al. (2011) © 2011 Demuro et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View

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