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Figure 5. Time course of BP block of BK channels in K+ and Rb+ solutions. Raw currents at the indicated potentials in the absence (black) and presence (red) of 2 µM BP recorded in 100 µM Ca2+ in K+ (left; calibration: 1.2 nA, 50 msec) and Rb+ (right; calibration: 0.25 nA, 50 msec) solutions. The holding potential for the K+ solutions was −80 mV. For the Rb+ solutions, the voltage level before depolarization was −100 mV, and after the depolarization it was −80 mV. The tail currents upon repolarization have been truncated for clarity. Image published in: Thompson J and Begenisich T (2012) © 2012 Thompson and Begenisich. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View

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