Xenbase Image ID: 127433

Figure 2. Comparison between apo Lin28 CSDs and oligonucleotide-bound Lin28 CSD. (A) Superimposition of apo XtrLin28b CSD (gray) and hLin28b CSD (orange). Highly conserved residues that are involved in nucleic acid binding are indicated in stick representation and marked according to their position within the XtrLin28b CSD. Gln69, which corresponds to a highly conserved Phe in bacterial CSPs, is indicated in red. (B) Cartoon representation of dT7 bound to XtrLin28b CSD. The aromatic side chains that are involved in direct stacking interactions with the dT7 bases are shown in stick representation. Image published in: Mayr F et al. (2012) © The Author(s) 2012. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license Larger Image Printer Friendly View

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