Xenbase Image ID: 127853

Figure 5. Mg-nucleotide activation of wild-type and mutant KATP channelsA and B, mean relationships between [MgADP] (A) or [MgATP] (B) and KATP conductance (G) expressed relative to that in the absence of nucleotide (Gc), for Kir6.2-G334D/SUR1 (o, n= 5) and Kir6.2-G334D/SUR1-G1401R (•, n= 5) channels. The lines through the G1401R data are drawn by eye. The lines through the wild-type data are drawn to eqn (2) with the following parameters: A: EC50= 38 μm, h= 2, a= 10; B: EC50= 196 μm, h= 1.6, a= 4.6. Image published in: de Wet H et al. (2012) Image downloaded from an Open Access article in PubMed Central. © 2012 The Authors. The Journal of Physiology © 2012 The Physiological Society Larger Image Printer Friendly View

Return to previous page