Xenbase Image ID: 128439

Figure 3. Non-methylated islands are a highly conserved epigenetic feature of vertebrate gene promoters.(A) The presence of NMIs at orthologous gene TSSs is preserved as illustrated by a pairwise analysis of NMIs at vertebrate gene orthologues. The percentage of NMIs conserved at orthologous gene TSSs was calculated in a pairwise manner and found to be highly statistically significant for all comparisons across the seven vertebrate species (p<10−10, hypergeometric test). (B) A proportional Venn diagram illustrating the three-way comparison of NMI presence at conserved human-mouse-zebrafish gene orthologue TSSs.DOI: http://dx.doi.org/10.7554/eLife.00348.006 Image published in: Long HK et al. (2013) Copyright © 2013, Long et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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