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Figure 6. Chromatin modification at NMIs depends on their underlying DNA methylation state.(A) H3K4me3 read density from testes (blue) and liver (red) is profiled over testes unique (left) and liver unique (right) NMIs for human (upper) and mouse (lower) and displayed as an average profile. At differentially methylated loci, the histone H3K4me3 modification is found preferentially in the tissue with the non-methylated NMI. (B) The H3K4me3 signal (profiled in frog stage 11–12 embryos and zebrafish 24 hpf) is present specifically at unique NMIs from frog stage 11–12 and zebrafish 24 hpf (green) and not at unique NMIs from the liver (red).DOI: http://dx.doi.org/10.7554/eLife.00348.012 Image published in: Long HK et al. (2013) Copyright © 2013, Long et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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