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Fig. 8. Transgenic OB tadpoles carrying anti-b2m shRNA are more susceptible to FV3 infections.(A) F0 transgenic tadpoles (stage 56, GFP+) carrying either a shRNA targeting b2m (Tg, 23 larvae) or WT (Control, 10 larvae) were infected with 5×106 PFU FV3 via the water route for 1 hour. (B) F0 transgenic tadpoles (stage 56, GFP+) carrying either a shRNA targeting b2m (Tg β2-m shRNA, 36 larvae) or a scrambled shRNA (Tg scram shRNA, 22 larvae) were infected with 5×106 PFU FV3 via the water route for 1 hour. Survival was monitored daily. P values were determined using the Student's t-test. Image published in: Nedelkovska H et al. (2013) © 2013. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license Larger Image Printer Friendly View |