Xenbase Image ID: 128652

FIGURE 2. (A) Representative traces showing the effect of increasing concentrations of 2-APB on hKCNK4-expressing (top) and hKCNK2-expressing (bottom) Xenopus oocytes subjected to the ramp series protocol described in the experimental procedures. (B) Representative I–V traces for the excitatory effect of increasing concentrations of 2-APB on oocytes expressing hKCNK2 (left) and hKCNK4 (right). (C) Dose–response curve showing the effects of 2-APB on hKCNK2 and fitted to the 4-parameter Hill equation (n indicated above the points). (D) Dose–response relationship showing the effect of 2-APB on hKCNK4 (n indicated above the points). (E) Dose–response relationship showing the effect of 2-APB on hKCNK4 (n = 3–5 HEK293 cells). (F) Inside-out patch-clamp recordings of cell-excised patches from hKCNK4-expressing HEK293 cells before and after exposure to 3 mM 2-APB. Image published in: Beltrán L et al. (2013) Copyright © Beltrán, Beltrán, Aguado, Gisselmann and Hatt. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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