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Figure 3. Loss of Mef2c or Mef2d affects the cardiac progenitor cell population.Mef2c or Mef2d MO (10 ng) was unilaterally injected and expression of cardiac marker genes was monitored at stage 20. A. tbx20 expression was down-regulated in Mef2c MO- or Mef2d MO-injected embryos (arrowheads). In addition, Mef2d- but not Mef2c-depleted embryos showed reduced tbx1 expression (arrowhead). Expression of isl1 as well as bmp4 remained unchanged upon loss of Mef2c or Mef2d. Anterior views of embryos are shown. B. Quantitative presentation of observed phenotypes in A is given. N: number of examined embryos; n: number of independent experiments; *, p≤0.05. Image published in: Guo Y et al. (2014) Image reproduced on Xenbase with permission of the publisher and the copyright holder. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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