Xenbase Image ID: 129751

Fig. 7. IRE1α knockdown inhibits pancreas marker gene expression.Whole mount in situ hybridization analyses revealed that the expression of insulin (B) and amylase (D) was not detected in 50 ng XBP1MO injected embryos at stage 43 compared with control MO injected embryos (A,C). The white arrows indicate positive staining. Image published in: Yuan L et al. (2014) Image downloaded from an Open Access article in PubMed Central. © 2014 by the Journal of Biomedical Research. All rights reserved. Gene Synonyms Species Stage(s) Tissue ins.L ins-a, ins-b, ins1, insulin, insulin I, preproinsulin, xins X. laevis Throughout NF stage 43 pancreas amy2a.L X. laevis Throughout NF stage 43 pancreas dorsal pancreatic bud ventral pancreatic bud Image source: Published Experiment + Assay Source Phenotypes and Disease Xla Wt + xbp1 MO + NF 43 Fig 7 B D Anatomical Phenotype abnormal foregut morphology abnormally coiled small intestine Expression Phenotype absent amy2a.L expression in pancreas absent ins.L expression in pancreas Larger Image Printer Friendly View

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