Xenbase Image ID: 129794

Figure 2. (a) Amino-acid sequences of XHMGA2 protein were compared with those of human (NM_001094371), mouse (NM_010441), rat (NM_032070), chicken (NM_205001) and zebrafish (NM_212680) HMGA2. Dots indicate identities and dashed lines are introduced to maximize the alignment. Boxes represent the three AT-hooks. (b) Expression of XHMGA2 mRNA during embryogenesis analysed by RT-PCR. Ornithine decarboxylase (ODC) represents internal controls. (c–h) Expression of XHMGA2 mRNA during embryogenesis analysed by in situ hybridization. Lateral (c) and ventral (d) view of stage-15 embryo. XHMGA2 expression was detected in neural crest (NC) and weakly in precardiac region (arrowhead). Lateral (e) and ventral (f) view of stage-23 embryo. XHMGA2 was expressed in anterior neural tissue (AN), tailbud (TB) and weakly in precardiac region (arrowhead). Lateral (g) and ventral (h) view of stage-32 embryo. XHMGA2 was detected in brain (BR), spinal cord (SC), eye anlage (EA), otic vesicle (OV), branchial arch (BA), pronephric duct (PD) and heart anlage (arrowhead). Anterior is left and dorsal is top for c, e, g, and anterior is left for d, f, h. Image published in: Monzen K et al. (2008) Copyright © 2008. Image reproduced with permission of the Publisher, Macmillan Publishers Ltd. Gene Synonyms Species Stage(s) Tissue hmga2.L X. laevis Throughout NF stage 15 neural crest neuroectoderm cardiac mesoderm hmga2.L X. laevis Throughout NF stage 23 cardiac mesoderm tail bud neural crest cranial neural crest pronephric mesenchyme neuroectoderm anterior placodal area hmga2.L X. laevis Throughout NF stage 32 heart cardiac mesoderm heart primordium pharyngeal arch mandibular arch hyoid arch branchial arch pronephric duct eye lens placode otic vesicle spinal cord tail tip chordoneural hinge tail brain forebrain midbrain hindbrain midbrain-hindbrain boundary secondary heart field primary heart field Image source: Published Larger Image Printer Friendly View

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