Xenbase Image ID: 129951

Figure 1. Lrp6 Is Basolaterally Localized in Xenopus Outer Ectodermal Cells (A–D) Confocal immunofluorescence microscopy of embryos at the indicated stages stained for endogenous Lrp6 (A), and at stage 9 stained for Lrp6, pLrp6 (B and C), or vesicle markers (D) (green). b1-integrin (red) delineates the basolateral membrane. Nuclei were counterstained with Hoechst (blue). White square in (B) marks the magnified area shown in (C). Arrow and dashed lines, apical membrane; arrowhead, basolateral membrane. Scale bars represent 30 mm. Experi- ments were typically carried out independently at least three times with similar results. For each experiment, more than 10 embryos per sample were analyzed. Image published in: Huang YL and Niehrs C (2014) Copyright © 2014. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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