XB-IMG-130643
Xenbase Image ID: 130643
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Figure 6. Combined Loss of Eomes, VegT, and Xbra Reveals Their Collaboration to Determine Neuromesodermal Bipotency and Promote Mesodermal Differentiation during Axial ElongationGastrula-staged snapshots of Eomes, VegT, and Xbra binding near mesoderm-specific genes myf5, myoD, msgn1, foxc1, mespa (A, B, and D–F), and neurogenic genes sox3 and pax3 (G and H). WMISH on control and indicated KD embryos for target genes (A, B, and D–H) and muscle-specific differentiation marker myosin heavy chain 1, myh1 (C). Cross-sections at positions of sox3 and pax3 WMISH as indicated. no, notochord; nt, neural tube (d, dorsal; v, ventral); hm, hypaxial muscle; pm, paraxial mesoderm; sm, skeletal muscle. The scale bar represents 0.2 mm. See also Figures S6 and S7. Image published in: Gentsch GE et al. (2013) Image downloaded from an Open Access article in PubMed Central. © 2013 The Authors Larger Image Printer Friendly View |
