Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-IMG-130816

Xenbase Image ID: 130816


Fig. 4. BMP-3b triggers head formation in an intrinsic developmental pathway. To examine head formation by BMP-3b, we performed lineage tracing and rescue of embryos exposed to UV. (A) Injection of rBMP-3b mRNA (1 ng) rescued anterior structure of UV-ventralized embryos. Cells expressing BMP-3b were localized in head region (60%, n 15). (B) Section of an embryo shown in (A). Cells were labeled in notochord (nt), heart (ht), optic cup, and adjacent to cement gland, suggesting that cells expressing BMP-3b differentiated into “head-forming cells” and organized head structures. (C) Cells expressing BVg1 (50 pg), an organizer inducer, were localized in endoderm, suggesting that they induced head-forming cells (50%, n 14; Thomsen and Melton, 1993). (D) Injection of cerberus (1 ng) led to formation of smaller head than that with BMP-3b (60%, n 25; Bouwmeester et al., 1996). (I) Control embryo.

Image published in: Hino J et al. (2003)

Copyright © 2003. Image reproduced on Xenbase with permission of the Publisher, Elsevier B. V.

Larger Image
Printer Friendly View

Return to previous page
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.11.1


Major funding for Xenbase is provided by grant P41 HD064556